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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes

for
Tobacco Products, Cigarettes, Electronic Cigarettes
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07599462

Recruiting

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

for
Cardiovascular Disease
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 30

Code: NCT06263452

Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for
Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma
Location: Greensboro NC, Charlotte NC, Charlottesville VA,
Sponsor: UroGen Pharma Ltd.

Sex: All

Age: 18+

Code: NCT06774131

Phase3, Recruiting

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for
Eosinophilic Esophagitis (EoE)
Location: Chapel Hill NC, Charlottesville VA, Charleston SC,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 0 - 6

Code: NCT07112378

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

for
Ulcerative Colitis
Location: Chapel Hill NC, Harrisburg PA, Marietta GA, New York NY,
Sponsor: Sanofi

Sex: All

Age: 18 - 70+

Code: NCT06975722

Phase2, Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for
Multiple Myeloma
Location: Chapel Hill NC, Winston-Salem NC, Charlotte NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06892522

Phase1, Phase2, Recruiting

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

for
Cancer, Diabetes
Location: Chapel Hill NC, Tampa FL, Burlington VT
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT07061652

Recruiting

PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients

for
Breast Cancer
Location: Chapel Hill NC, Richmond VA
Sponsor: Endomagnetics Ltd.

Sex: All

Age: 18+

Code: NCT06610539

Recruiting

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Chapel Hill NC, Midlothian VA, Richmond VA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase3, Recruiting

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

for
Oncology, Myeloid Leukemia, Acute, Cancer
Location: Chapel Hill NC, Winston-Salem NC, Birmingham AL,
Sponsor: University of Rochester

Sex: All

Age: 60+

Code: NCT06697600

Recruiting

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for
Major Depressive Disorder
Location: Cary NC, Baltimore MD, Atlanta GA, Toms River NJ,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07076407

Phase3, Recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

for
Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS),
Location: Chapel Hill NC, Columbus OH, New York NY, Boston MA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT06465953

Phase3, Recruiting

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

for
Barrett Esophagus,
Location: Chapel Hill NC, Ann Arbor MI, St Louis MO, Dallas TX
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06732388

Phase2, Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for
Relapsing Multiple Sclerosis
Location: Raleigh NC, Richmond VA, Greenville SC,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 40 - 70

Code: NCT06846281

Phase3, Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for
Buccal Mucosa Squamous Cell Carcinoma,
Location: Chapel Hill NC, Charleston SC, York PA, Carlisle PA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT04333537

Phase2, Phase3, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Chapel Hill NC, Pinehurst NC, Kernersville NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase3, Recruiting

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

for
Prostate Cancer, Kidney Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06965192

Recruiting

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

for
Recurrent Chronic Lymphocytic Leukemia,
Location: Chapel Hill NC, Pittsburgh PA, Columbus OH, Boston MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07061951

Phase2, Recruiting

Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise

for
Breast Cancer, Metastatic Breast Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07313306

Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Chapel Hill NC, Concord NC, Charlotte NC, Charleston SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07195734

Phase2, Recruiting