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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Chicago IL, Providence RI, Westerly RI, Waterford CT,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 60+

Code: NCT05976763

Phase3, Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for
Neoplasms
Location: Boston MA, North Worcester MA, New Haven CT,
Sponsor: Celgene

Sex: All

Age: 0+

Code: NCT03435796

Phase2, Phase3, Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Montreal, Hershey PA, Chapel Hill NC, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase2, Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

for
Advanced Non-Small Cell Lung Cancer,
Location: South Weymouth MA, Boston MA, Brighton MA,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04613596

Phase2, Phase3, Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for
Ganglioneuroblastoma, Nodular, Neuroblastoma
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 30

Code: NCT06172296

Phase3, Recruiting

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Digital Art Therapy for Young Cancer Survivors

for
Cancer, Pediatric Cancer, Pediatric Malignancies,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 25

Code: NCT06789666

Recruiting

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for
Smoldering Plasma Cell Myeloma
Location: York Village ME, Boston MA, Westerly RI, Waterford CT,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT03937635

Phase3, Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for
Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors
Location: Augusta ME, Brewer ME, Rockport ME, Belfast ME,
Sponsor: American Society of Clinical Oncology

Sex: All

Age: 12+

Code: NCT02693535

Phase2, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Portland ME, Scarborough ME, South Portland ME,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase3, Recruiting

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

for
Sarcoma, Bone Metastases, Proximal Femur Replacement
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 16 - 70+

Code: NCT03261544

Recruiting

The Myelin Disorders Biorepository Project

for
Leukodystrophy, White Matter Disease, Leukoencephalopathies,
Location: Boston MA, Philadelphia PA, Baltimore MD,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT03047369

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Boston MA, New Haven CT, Lebanon NH, Mineola NY,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for
Peripheral Arterial Diseases
Location: Boston MA, Baltimore MD, Chapel Hill NC, Cleveland OH,
Sponsor: Angiodynamics, Inc.

Sex: All

Age: 0+

Code: NCT06777901

Recruiting

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Brewer ME, Westerly RI, Manchester NH, Worcester MA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05642572

Phase2, Recruiting

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

for
Renal Pelvis and Ureter Urothelial Carcinoma
Location: Augusta ME, Scarborough ME, South Portland ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04628767

Phase2, Phase3, Recruiting

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

for
Hematopoietic Stem Cell Transplant, CAR-T Cell Therapy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT06575712

Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Halifax, Saint John, Boston MA, Providence RI,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

Project: Every Child for Younger Patients With Cancer

for
Adrenal Gland Pheochromocytoma, Carcinoma In Situ,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT02402244

Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Boston MA, Providence RI, Lebanon NH, Quebec,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase3, Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for
Acute Respiratory Distress Syndrome (ARDS), ARDS,
Location: Burlington MA, The Bronx NY, New Brunswick NJ,
Sponsor: PPD Development, LP

Sex: All

Age: 18+

Code: NCT06701669

Phase2, Recruiting

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