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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

for
Hemolytic Disease of the Fetus and Newborn
Location: Boston MA, New York NY, Montreal, Allentown PA,
Sponsor: Janssen Research & Development, LLC

Sex: Female

Age: 18 - 45

Code: NCT05912517

Phase3, Recruiting

Anesthetics and Analgesics in Children

for
Anesthesia, Pain
Location: Durham NC, Charleston SC, Toronto, Chicago IL,
Sponsor: Chi Dang Hornik

Sex: All

Age: 0 - 17

Code: NCT03427736

Recruiting

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: New York NY, Baltimore MD, Fairfax VA, Durham NC,
Sponsor: Pathos AI, Inc.

Sex: Male

Age: 18+

Code: NCT06785636

Phase1, Phase2, Recruiting

Cognitive and Neurological Pathologies in Pompe Disease

for
Pompe Disease
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0 - 18

Code: NCT04639336

Recruiting

Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

for
Juvenile Psoriatic Arthritis
Location: New York NY, Pittsburgh PA, Charlotte NC,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 2 - 17

Code: NCT06751238

Phase1, Recruiting

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Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial

for
Shoulder Dislocation, Glenohumeral Dislocation,
Location: Providence RI, Annapolis MD, Durham NC, Chapel Hill NC,
Sponsor: University of Pittsburgh

Sex: All

Age: 17 - 50

Code: NCT04809064

Recruiting

Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes

for
Penile Implantation, Infections
Location: Philadelphia PA, Raleigh NC, Bossier City LA
Sponsor: MicroGenDX

Sex: Male

Age: 18 - 70+

Code: NCT05287438

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

for
Community-acquired Pneumonia
Location: Mount Kisco NY, Winston-Salem NC, Houston TX, Fresno CA
Sponsor: Biotest

Sex: All

Age: 18+

Code: NCT05722938

Phase3, Recruiting

Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma

for
Head and Neck Neoplasm, Carcinoma, Squamous Cell
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04099290

Recruiting

Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System

for
Focal Segmental Glomerulosclerosis
Location: New York NY, Wilmington DE, Richmond VA, Chapel Hill NC,
Sponsor: Kaneka Medical America LLC

Sex: All

Age: 0 - 70+

Code: NCT04065438

Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Boston MA, Providence RI, New York NY, Hackensack NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for
Hemorrhagic Shock, Trauma Injury
Location: Washington D.C. DC, Wake Forest NC, Pittsburgh PA,
Sponsor: Philip Spinella

Sex: All

Age: 0 - 17

Code: NCT06070350

Phase3, Recruiting

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for
Advanced Solid Tumors Cancer, MSI-H Cancer
Location: Providence RI, Fairfax VA, Charlottesville VA,
Sponsor: Nimbus Wadjet, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06898450

Phase1, Phase2, Recruiting

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

for
Major Depressive Disorder
Location: Boston MA, Cromwell CT, Springfield MA, Brooklyn NY,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT06775379

Phase3, Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for
B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma,
Location: Valhalla NY, Chapel Hill NC, Jacksonville FL,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 13 - 70+

Code: NCT06533579

Phase1, Phase2, Recruiting

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for
Relapsed or Refractory Multiple Myeloma (RRMM)
Location: Halifax, Boston MA, New York NY, Montreal,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06615479

Phase3, Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for
Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma,
Location: New Haven CT, The Bronx NY, New York NY,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: All

Age: 18+

Code: NCT01042379

Phase2, Recruiting

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for
Low Grade Serous Ovarian Cancer
Location: New Haven CT, New York NY, Montreal, Philadelphia PA,
Sponsor: Verastem, Inc.

Sex: Female

Age: 18+

Code: NCT06072781

Phase3, Recruiting

Pharmacokinetics of Drugs Administered to Children

for
Pediatric ALL
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0 - 20

Code: NCT03481881

Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for
Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis,
Location: Boston MA, New Haven CT, Rosedale NY, New York NY,
Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All

Age: 18 - 70+

Code: NCT06563895

Phase3, Recruiting

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