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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Development & Validation of Preoperative Objective Physiological Evaluation

for
Cardiorespiratory Fitness
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05092126

Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase1, Phase2, Recruiting

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial

for
Recurrent Glioblastoma
Location: Durham NC, Salt Lake City UT, San Francisco CA
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06069726

Phase2, Recruiting

Study of Trilaciclib and Lurbinectidin

for
Lung Cancer, Small-cell Lung Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05578326

Phase2, Recruiting

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

for
Sickle Cell Disease, Thalassemia
Location: New York NY, Durham NC, Atlanta GA, Chicago IL,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 2+

Code: NCT06609226

Phase3, Recruiting

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Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for
Focal Segmental Glomerulosclerosis
Location: New York NY, Philadelphia PA, Wilmington DE,
Sponsor: Kaneka Medical America LLC

Sex: All

Age: 0 - 21

Code: NCT02235857

Recruiting

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for
Melanoma, Cutaneous Malignant
Location: Boston MA, New Haven CT, New York NY, Morristown NJ,
Sponsor: Immatics US, Inc.

Sex: All

Age: 18+

Code: NCT06743126

Phase3, Recruiting

Primary Subtalar Arthrodesis for Calcaneal Fractures

for
Calcaneus Fracture
Location: Baltimore MD, Chapel Hill NC, Concord NC, Charlotte NC,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06249126

Recruiting

Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting

for
Pressure Ulcers
Location: Durham NC
Sponsor: Precision Fabrics Group, Inc.

Sex: All

Age: 0+

Code: NCT01355666

Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for
Colorectal Neoplasms
Location: Shirley NY, New Haven CT, Mineola NY, The Bronx NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06662786

Phase3, Recruiting

Generic Database of Very Low Birth Weight Infants

for
Infant, Newborn, Infant, Low Birth Weight,
Location: Philadelphia PA, Durham NC, Cleveland OH, Atlanta GA,
Sponsor: NICHD Neonatal Research Network

Sex: All

Age: 0

Code: NCT00063063

Recruiting

Muscle Fiber Fragment Treatment for Urinary Incontinence

for
Urinary Incontinence
Location: Winston-Salem NC
Sponsor: Wake Forest University

Sex: Female

Age: 18 - 70+

Code: NCT01953263

Phase1, Phase2, Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

for
Beta-Thalassemia, Thalassemia, Hematologic Diseases,
Location: New York NY, Charlotte NC, Nashville TN
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 12 - 35

Code: NCT05477563

Phase3, Recruiting

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for
B-cell Malignancy, Chronic Lymphocytic Leukemia,
Location: Worcester MA, Westbury NY, Baltimore MD, Durham NC,
Sponsor: Carna Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05602363

Phase1, Recruiting

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Clasp Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06778863

Phase1, Recruiting

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for
Metastatic Non Small Cell Lung Cancer
Location: New York NY, Montreal, Camden NJ, Richmond VA,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT04614103

Phase2, Recruiting

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

for
Aneurysm, Dissection, Aortic Root Aneurysm,
Location: Philadelphia PA, Allentown PA, Greenville NC,
Sponsor: Vascutek Ltd.

Sex: All

Age: 18+

Code: NCT04545502

Recruiting

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

for
NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer,
Location: New Haven CT, Lebanon NH, The Bronx NY, New York NY,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06881784

Phase3, Recruiting

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

for
Sickle Cell Disease
Location: Boston MA, Queens NY, The Bronx NY, Brooklyn NY,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 12+

Code: NCT06612268

Phase3, Recruiting

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

for
Hearing Loss, Emergency Service, Hospital Readmission
Location: The Bronx NY, New York NY, Durham NC, Aurora CO
Sponsor: VA Office of Research and Development

Sex: All

Age: 60+

Code: NCT05028972

Recruiting

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