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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for
Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma,
Location: Miami FL, Huntersville NC, Grand Rapids MI,
Sponsor: Aulos Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05267626

Phase1, Phase2, Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for
Metastatic Breast Cancer
Location: Boston MA, New York NY, New Brunswick NJ, Montreal,
Sponsor: LeonaBio

Sex: All

Age: 18+

Code: NCT05696626

Phase3, Recruiting

The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families

for
Parent Child Relationship, Child Social-Emotional Development,
Location: Raleigh NC
Sponsor: University of Washington

Sex: Female

Age: 18+

Code: NCT06740266

Recruiting

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

for
Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma,
Location: Durham NC, Ann Arbor MI, Houston TX, Dallas TX,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05563766

Phase2, Recruiting

Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

for
B-Cell Non-Hodgkin Lymphoma, Multiple Myeloma
Location: Winston-Salem NC, Columbus OH, Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06052826

Phase2, Recruiting

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TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

for
Breast Cancer, HER2-low Breast Cancer, Metastatic Breast Cancer,
Location: Boston MA, New Haven CT, The Bronx NY,
Sponsor: Ana C Garrido-Castro, MD

Sex: All

Age: 18+

Code: NCT06533826

Phase2, Recruiting

Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Baltimore MD, Pinehurst NC, Athens GA, Glendale CA
Sponsor: Teligene US

Sex: All

Age: 18+

Code: NCT05168566

Phase2, Recruiting

Optimizing Surgical Decisions in Young Adults With Breast Cancer

for
Breast Cancer Stage 0, Breast Cancer Stage I,
Location: Boston MA, New Haven CT, New York NY, Durham NC
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 44

Code: NCT06275126

Recruiting

Apathy in Parkinson Disease TMS Study

for
Parkinson Disease
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 55 - 70+

Code: NCT06087926

Recruiting

Embo Registry; National Registry for Artery Embolization

for
Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb,
Location: Cary NC, Winchester TN
Sponsor: Vascular Solutions of North Carolina

Sex: All

Age: 18+

Code: NCT06477965

Recruiting

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

for
Posttraumatic Stress Disorder
Location: Boston MA, Durham NC, Cincinnati OH
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05267665

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

for
Postoperative Pain
Location: Durham NC, Indianapolis IN, St Louis MO, Houston TX,
Sponsor: Pacira Pharmaceuticals, Inc

Sex: All

Age: 0 - 6

Code: NCT06271265

Phase1, Recruiting

Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for
PSMA PET-Positive Castration-Resistant Prostate Cancer
Location: Boston MA, New York NY, Durham NC, Cleveland OH,
Sponsor: Convergent Therapeutics

Sex: Male

Age: 18+

Code: NCT06549465

Phase2, Recruiting

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for
Heart Failure, Heart Failure With Reduced Ejection Fraction
Location: Bangor ME, Boston MA, Hartford CT, New Haven CT,
Sponsor: Cytokinetics

Sex: All

Age: 18 - 70+

Code: NCT06736574

Phase3, Recruiting

Case Series on the Clinical Performance of VA Clavicle and Clavicle Hook Plate 2.7 Systems

for
Clavicle, Acromioclavicular Joint, Fracture
Location: Winston-Salem NC, Columbia SC, Grand Rapids MI
Sponsor: AO Innovation Translation Center

Sex: All

Age: 18+

Code: NCT04921865

Recruiting

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Charlotte NC, Memphis TN, Tulsa OK
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06533748

Phase2, Recruiting

Brain Slice Explants to Predict Drug Response in Brain Tumors

for
Central Nervous System Tumor
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 0+

Code: NCT05978557

Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for
Neoplasms
Location: The Bronx NY, New York NY, East Brunswick NJ,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06150157

Phase1, Recruiting

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

for
Advanced Solid Tumor, Cutaneous T-cell Lymphoma (CTCL)
Location: Huntersville NC
Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT05569057

Phase1, Recruiting

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for
Spinal Muscular Atrophy (SMA)
Location: Farmington CT, New Haven CT, Stony Brook NY,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04174157

Recruiting

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