Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.
From paid studies for healthy volunteers to condition-specific trials, North Carolina offers a wide range of clinical research opportunities. Leading medical centers in Charlotte, Raleigh, and Durham are seeking participants, providing access to innovative treatments and comprehensive care.
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
for
Atrial Fibrillation
Location: Halifax, Sherbrooke, New York NY, Montreal, Camden NJ,
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07217067
Phase2, Recruiting
Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation
for
Cardiac Rehabilitation, Heart Disease
Location: Durham NC
Sponsor: Duke University
Sex: All
Age: 18+
Code: NCT07214350
Recruiting
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
for
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Sponsor: University of North Carolina, Chapel Hill
Sex: All
Age: 18 - 70+
Code: NCT07095036
Recruiting
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Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
for
GRIN-related Neurodevelopmental Disorder
Location: Boston MA, New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: GRIN Therapeutics, Inc.
Sex: All
Age: 0 - 18
Code: NCT07224581
Phase3, Recruiting
Comparison of Urinary Flow Study
for
Urinary Retention
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences
Sex: Female
Age: 18+
Code: NCT06918067
Recruiting
Timing of Physician Rounds for Antepartum Patients
for
Physician Rounds, Communication
Location: Durham NC
Sponsor: Duke University
Sex: Female
Age: 18+
Code: NCT07215507
Recruiting
Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS
for
Relapsed Acute Myeloid Leukemia (AML),
Location: Philadelphia PA, Chapel Hill NC, Columbus OH,
Sponsor: Auron Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06846606
Phase1, Recruiting
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Durham NC, Cleveland OH,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.
Sex: All
Age: 18+
Code: NCT06859762
Phase1, Recruiting
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
for
Atrial Fibrillation (AF)
Location: Moncton, Rimouski, Boston MA, Quebec, Sherbrooke,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07175428
Phase2, Recruiting
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
for
Uncontrolled Hypertension
Location: Boston MA, Waterbury CT, The Bronx NY, Vienna VA,
Sponsor: Retension Pharmaceuticals. Inc.
Sex: All
Age: 18 - 70
Code: NCT07142356
Phase2, Recruiting
Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2
for
Bladder Cancer, Recurrent Bladder Cancer,
Location: Chapel Hill NC, Tampa FL, Columbus OH, Nashville TN,
Sponsor: University of Washington
Sex: All
Age: 18+
Code: NCT07225127
Recruiting
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
for
Locally Advanced Adrenal Cortical Carcinoma,
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 12+
Code: NCT06900595
Phase2, Recruiting
Safer Drinking Spaces Study
for
Sexual Violence, Bystander Intervention
Location: Durham NC, Gainesville FL, Little Rock AR
Sponsor: RTI International
Sex: All
Age: 18+
Code: NCT07527988
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
for
Obesity, Overweight, Diabetes Mellitus, Type 2
Location: East Greenwich RI, Trenton NJ, Morehead City NC,
Sponsor: Amgen
Sex: All
Age: 18 - 70+
Code: NCT07684144
Phase3, Recruiting
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
for
Pulmonary Embolism
Location: Washington D.C. DC, Chapel Hill NC, Naples FL,
Sponsor: Innova Vascular, Inc.
Sex: All
Age: 18 - 70+
Code: NCT06041594
Recruiting
Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain
for
Tobacco Use, Chronic Pain
Location: Durham NC
Sponsor: Duke University
Sex: All
Age: 21 - 65
Code: NCT06983678
Recruiting
Downstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma
for
Severe Asthma
Location: Durham NC
Sponsor: Bastiaan Driehuys
Sex: All
Age: 18 - 65
Code: NCT07139899
Recruiting
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
for
Breast Neoplasms
Location: Westbrook ME, Burlington MA, New York NY,