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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

for
Type-2 Diabetes Mellitus
Location: Chapel Hill NC, Scottsdale AZ, Newport Beach CA
Sponsor: Aqua Medical, Inc.

Sex: All

Age: 22 - 65

Code: NCT07355270

Recruiting

LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

for
Sarcoma
Location: Winston-Salem NC, Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 0+

Code: NCT06958107

Recruiting

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

for
Acute Compartment Syndrome, Fracture, Bone, Tibial Fractures
Location: Baltimore MD, Charlotte NC, Nashville TN,
Sponsor: Major Extremity Trauma Research Consortium

Sex: All

Age: 18 - 60

Code: NCT05889559

Recruiting

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: Boston MA, Montreal, Philadelphia PA, Fairfax VA,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07094113

Phase1, Recruiting

ELEVATE-HFpEF Clinical Study

for
Heart Failure With Preserved Ejection Fraction (HFpEF)
Location: Boston MA, Hartford CT, Burlington VT, Wynnewood PA,
Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All

Age: 40+

Code: NCT06678841

Recruiting

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Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Scarborough ME, Stony Brook NY, White Plains NY,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase3, Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

for
Colon Cancer, Pancreatic Cancer, Lung Cancer (NSCLC),
Location: Boston MA, Washington D.C. DC, Fairfax VA, Durham NC,
Sponsor: Pheon Therapeutics

Sex: All

Age: 18+

Code: NCT07127874

Phase1, Recruiting

ATHNdataset Registry

for
Hemophilia, Thrombosis, Hemophilia A, Hemophilia B,
Location: Hickory NC
Sponsor: American Thrombosis and Hemostasis Network

Sex: All

Age: 0+

Code: NCT06820515

Recruiting

PRoducing Outcome Measures for OTP Quality Improvement

for
Opioid Use Disorder
Location: Research Triangle Park NC
Sponsor: RTI International

Sex: All

Age: 18+

Code: NCT07214389

Recruiting

Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

for
Chronic Lymphocytic Leukemia, Richter's Transformation
Location: Boston MA, Chapel Hill NC, Columbus OH, Atlanta GA
Sponsor: Christine Ryan

Sex: All

Age: 18+

Code: NCT06043674

Phase2, Recruiting

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1

for
Narcolepsy Type 1
Location: Newton MA, Middletown NJ, Wyomissing PA, Miami FL,
Sponsor: Alkermes, Inc.

Sex: All

Age: 18 - 70

Code: NCT07455383

Phase3, Recruiting

Bowel Continence Across the Lifespan in People With Spina Bifida

for
Spina Bifida, Neurogenic Bowel, Bowel Incontinence
Location: Boston MA, Philadelphia PA, Washington D.C. DC,
Sponsor: David Chu

Sex: All

Age: 5+

Code: NCT07390318

Recruiting

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Toronto, Huntersville NC, Galveston TX, San Antonio TX
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07360314

Phase1, Recruiting

ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

for
Dravet Syndrome
Location: Montreal, Durham NC, Ann Arbor MI, Memphis TN,
Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All

Age: 2 - 12

Code: NCT07531745

Phase1, Phase2, Recruiting

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

for
Narcolepsy Type 2
Location: Newton MA, Wyomissing PA, Maimi FL, Markham, Toronto,
Sponsor: Alkermes, Inc.

Sex: All

Age: 18 - 70

Code: NCT07502443

Phase3, Recruiting

Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices

for
Chronic Pelvic Pain Syndrome, Pelvic Pain, Pelvic Varices,
Location: New Hyde Park NY, New York NY, Chapel Hill NC
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 70+

Code: NCT06168058

Recruiting

Enhancing Wellness Through Affirming Services and Education

for
HIV, Mental Health Disorder, Substance Use
Location: Charlotte NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05700474

Recruiting

Study of Olutasidenib and Temozolomide in HGG

for
High Grade Glioma, Astrocytoma, Astrocytoma, Grade III,
Location: Durham NC, Miami FL, Columbus OH, Cincinnati OH,
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 12 - 39

Code: NCT06161974

Phase2, Recruiting

Pre-malignant States to Hematologic Malignancies in Firefighters

for
Clonal Hematopoiesis of Indeterminate Potential,
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 40 - 49

Code: NCT06870760

Recruiting

A New Intervention to Improve Function in Veterans With Anxiety and Depression

for
Anxiety and Depression
Location: Durham NC
Sponsor: VA Office of Research and Development

Sex: All

Age: 18 - 65

Code: NCT06188923

Phase2, Recruiting

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