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Paid Clinical Trials Columbus

Discover 1,294 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Columbus OH, Beavercreek OH, Liberty Township OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase3, Recruiting
Featured

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for
Neovascular Age-related Macular Degeneration
Location: Columbus OH, Dublin OH, Cleveland OH, Carmel IN,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07007065

Phase3, Recruiting
Featured

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

for
Diabetic Retinopathy
Location: Columbus OH, Oak Forest IL, Glendale CA
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07588100

Phase1, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Columbus OH, Dayton OH, Liberty Township OH,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Location: Columbus OH, Rochester MN, Salt Lake City UT
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05091424

Phase1, Recruiting

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Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for
Obesity or Overweight, Type 2 Diabetes Mellitus
Location: Columbus OH, Pittsburgh PA, Winston-Salem NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351058

Phase3, Recruiting
Featured

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for
Crohn's Disease
Location: Columbus OH, Cincinnati OH, Lexington KY,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT06548542

Phase2, Recruiting
Featured

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for
Huntington Disease
Location: Columbus OH, Cincinnati OH, Pittsburgh PA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 25 - 65

Code: NCT06826612

Phase1, Phase2, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Columbus OH, Ann Arbor MI, Chicago IL, Warrenville IL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase2, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Columbus OH, Farmington Hills MI, London, Chicago IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Columbus OH, Pittsburgh PA, Farmington Hills MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase3, Recruiting
Featured

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for
Non Small Cell Lung Carcinoma
Location: Columbus OH, Fort Wayne IN, Detroit MI, Hinsdale IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06772623

Phase1, Phase2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Columbus OH, Kettering OH, Cleveland OH, Fort Wayne IN,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for
Ovarian Cancer
Location: Hilliard OH, Lexington KY, Morgantown WV, Detroit MI,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT07059845

Phase2, Recruiting
Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Columbus OH, West Chester OH, Cincinnati OH,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for
Atopic Dermatitis
Location: Canal Winchester OH, Fairborn OH, Indianapolis IN,
Sponsor: AbbVie

Sex: All

Age: 2 - 11

Code: NCT06461897

Phase3, Recruiting
Featured

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non-Small Cell Lung Cancer
Location: Zanesville OH, Perrysburg OH, Chicago IL, Niles IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06568939

Phase2, Recruiting
Featured

A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia Areata

for
Severe Alopecia Areata
Location: Fairborn OH, Indianapolis IN, Omaha NE, Miami FL,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT07772492

Phase3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Beavercreek OH, Cleveland OH, Louisville KY, London,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting
Active & Responsive

A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants

for
Systemic Lupus Erythematosus
Location: Columbus OH, Aurora CO, Las Vegas NV
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 65

Code: NCT06576271

Phase1, Recruiting