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Paid Clinical Trials Columbus

Discover 1,289 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

for
Chronic Inflammatory Demyelinating Polyneuropathy
Location: Columbus OH, Cincinnati OH, Indianapolis IN,
Sponsor: Dianthus Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06858579

Phase3, Recruiting

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

for
Transthyretin-Mediated Amyloidosis, ATTR Amyloidosis
Location: Columbus OH, Baltimore MD, Durham NC, Philadelphia PA,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04561518

Recruiting

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

for
Coronary Artery Disease
Location: Columbus OH, Cincinnati OH, Indianapolis IN, York PA,
Sponsor: Kardion Inc

Sex: All

Age: 18 - 70+

Code: NCT06445608

Recruiting

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for
Mantle Cell Lymphoma, B Cell Lymphoma
Location: Columbus OH, Cleveland OH, Fort Wayne IN, Ann Arbor MI,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06742996

Phase3, Recruiting

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

for
Neuromyelitis Optica Spectrum Disorder, NMOSD, AQP4+ NMOSD
Location: Columbus OH, Washington D.C. DC, Milwaukee WI,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05966467

Recruiting

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A Prospective Sub-Study of the Global Hypophosphatasia Registry

for
Hypophosphatasia
Location: Columbus OH, Chicago IL, Charlottesville VA,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 0+

Code: NCT05234567

Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for
Non-Small Cell Lung Cancer
Location: Columbus OH, Cincinnati OH, Cleveland OH, Lexington KY,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT06767514

Phase3, Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

for
Non-Small Cell Lung Cancer
Location: Columbus OH, Cincinnati OH, Canton OH, Maumee OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05236114

Recruiting

EFS of the DUO System for Tricuspid Regurgitation

for
Tricuspid Regurgitation, Tricuspid Valve Insufficiency,
Location: Columbus OH, Chicago IL, Harrisburg PA, Atlanta GA,
Sponsor: CroiValve Limited

Sex: All

Age: 18+

Code: NCT05913908

Recruiting

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

for
Pulmonary Embolism
Location: Columbus OH, Knoxville TN, Washington D.C. DC,
Sponsor: Innova Vascular, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06041594

Recruiting

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

for
Symptomatic Venous Thromboembolism (VTE)
Location: Columbus OH, Cincinnati OH, Pittsburgh PA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07213778

Phase3, Recruiting

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for
Obesity, Overweight, Chronic Weight Management,
Location: Columbus OH, Manassas VA, Winston-Salem NC,
Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07654374

Phase3, Recruiting

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

for
Obesity, Overweight, Chronic Weight Management
Location: Columbus OH, Silver Spring MD, Charlotte NC,
Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07654361

Phase3, Recruiting

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for
Weight Management
Location: Columbus OH, Dayton OH, Louisville KY, Sarnia,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07667803

Phase3, Recruiting

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

for
Overweight or Obese Adults,
Location: Columbus OH, Miami FL
Sponsor: Alveus Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT07399678

Phase1, Recruiting

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for
Acute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)
Location: Columbus OH, Cincinnati OH, Maumee OH, Bethesda MD,
Sponsor: Tempus AI

Sex: All

Age: 0+

Code: NCT07154823

Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

for
Prosthetic-joint Infection
Location: Columbus OH, Cincinnati OH, Cleveland OH, Morgantown WV,
Sponsor: Peptilogics

Sex: All

Age: 18 - 70+

Code: NCT07214311

Phase2, Phase3, Recruiting

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for
Breast Cancer, Locally Advanced Breast Cancer,
Location: Columbus OH, Cincinnati OH, Urbana IL, Toronto,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07085767

Phase3, Recruiting

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for
Aortic Dissection
Location: Columbus OH, Cleveland OH, Morgantown WV, Pittsburgh PA,
Sponsor: W.L.Gore & Associates

Sex: All

Age: 18+

Code: NCT06827990

Recruiting

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for
Asthma
Location: Columbus OH, Dayton OH, Findlay OH, Toledo OH,
Sponsor: AstraZeneca

Sex: All

Age: 12 - 17

Code: NCT06307665

Phase3, Recruiting