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Paid Clinical Trials Toledo

Discover 754 paid clinical trials in Toledo, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for
Aortic Valve Insufficiency, Aortic Valve Stenosis
Location: Detroit MI, Cleveland OH, Cincinnati OH, Pittsburgh PA,
Sponsor: Edwards Lifesciences

Sex: All

Age: 0+

Code: NCT05172973

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for
Metastatic Castration-resistant Prostate Cancer (mCRPC),
Location: Detroit MI, Cleveland OH, Grand Rapids MI, Carmel IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136650

Phase3, Recruiting

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for
Sickle Cell Trait
Location: Detroit MI, Columbus OH, Indianapolis IN, Wilmington DE,
Sponsor: National Alliance for Sickle Cell Centers

Sex: All

Age: 18+

Code: NCT06071377

Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for
Acute Respiratory Distress Syndrome, ARDS
Location: Detroit MI, Cleveland OH, Silver Spring MD,
Sponsor: Direct Biologics, LLC

Sex: All

Age: 18 - 70+

Code: NCT05354141

Phase3, Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

for
Clear Cell Renal Cell Carcinoma, Solid Tumors
Location: Detroit MI, Cleveland OH, Pittsburgh PA, Louisville KY,
Sponsor: Arcus Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05536141

Phase1, Recruiting

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SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects

for
Cystic Fibrosis
Location: Detroit MI, Cleveland OH, Columbus OH, Chicago IL,
Sponsor: Aridis Pharmaceuticals, Inc.

Sex: All

Age: 18 - 49

Code: NCT03669614

Phase1, Phase2, Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Detroit MI, Columbus OH, London, Toronto, Fairfax VA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase1, Phase2, Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

for
Relapsed AL Amyloidosis, Refractory AL Amyloidosis,
Location: Detroit MI, Cleveland OH, Toronto, St Louis MO,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07081646

Phase1, Phase2, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Detroit MI, Cleveland OH, Cincinnati OH, Chicago IL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for
Primary Biliary Cholangitis
Location: Detroit MI, Cleveland OH, Columbus OH, Pittsburgh PA,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06051617

Phase3, Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for
AChR-Ab Seropositive Generalized Myasthenia Gravis,
Location: Detroit MI, Columbus OH, Amherst NY, Durham NC,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07284420

Phase2, Recruiting

Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

for
Bipolar I Disorder
Location: Detroit MI, Canton OH, Chicago IL, St Louis MO,
Sponsor: LB Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07494305

Phase2, Recruiting

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for
Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
Location: Southfield MI, Sterling Heights MI, Cleveland OH,
Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All

Age: 18 - 65

Code: NCT06752668

Phase2, Recruiting

A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

for
Hearing Loss, Bilateral Sensorineural
Location: Novi MI, Beachwood OH, St Louis MO, Iowa City IA,
Sponsor: Cochlear

Sex: All

Age: 18+

Code: NCT07287124

Recruiting

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

for
Narcolepsy Type 1
Location: Novi MI, Cleveland OH, Dublin OH, Cincinnati OH,
Sponsor: Takeda

Sex: All

Age: 16 - 70

Code: NCT05816382

Phase2, Phase3, Recruiting

MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

for
Degenerative Disc Disease, Spine Fusion,
Location: Bloomfield Hills MI, Columbus OH, Chicago IL,
Sponsor: Kuros Biosurgery AG

Sex: All

Age: 18+

Code: NCT05037968

Recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for
Graves' Disease
Location: Farmington Hills MI, Flint MI, Canton OH,
Sponsor: Immunovant Sciences GmbH

Sex: All

Age: 18 - 70+

Code: NCT06727604

Phase2, Recruiting

Persona Revision Knee System Outcomes

for
Arthroplasty Complications, Infection, Knee Disease,
Location: Southfield MI, Rochester MI, Cleveland OH, Granger IN,
Sponsor: Zimmer Biomet

Sex: All

Age: 18+

Code: NCT04821154

Recruiting

A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)

for
Sarcoma,Soft Tissue
Location: Farmington Hills MI, Columbus OH, Toronto,
Sponsor: Intensity Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06263231

Phase3, Recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for
Multiple Sclerosis Spasticity
Location: Southfield MI, Columbus OH, London, Cincinnati OH,
Sponsor: Celgene

Sex: All

Age: 18 - 70

Code: NCT06782490

Phase2, Recruiting