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Paid Clinical Trials Ontario

Discover 2,717 paid clinical trials in Ontario. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis

for
Colitis, Ulcerative
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 18 - 64

Code: NCT06660693

Phase3, Recruiting
Active & Responsive

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for
Atopic Dermatitis
Location: Fredericton, Quebec, New York NY, Montreal,
Sponsor: Apogee Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07003425

Phase2, Recruiting
Active & Responsive

Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

for
Scleroderma, Systemic, Digital Ulcer
Location: Ottawa, Toronto, London, Calgary
Sponsor: Primus Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06256575

Recruiting
Active & Responsive

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for
Huntington Disease
Location: Boston MA, Farmington CT, New York NY, Burlington VT,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 21 - 70

Code: NCT07326709

Phase3, Recruiting

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Active & Responsive

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for
Geographic Atrophy Secondary to Age-related Macular Degeneration,
Location: Boston MA, New York NY, Toms River NJ, Philadelphia PA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 50+

Code: NCT07441642

Phase2, Recruiting
Active & Responsive

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia

for
Chronic Myeloid Leukemia,
Location: The Bronx NY, New York NY, Toronto, Houston TX,
Sponsor: Enliven Therapeutics

Sex: All

Age: 18+

Code: NCT05304377

Phase1, Recruiting
Active & Responsive

Left vs. Right Non-Inferiority Trial

for
Depression, Major Depressive Disorder, Major Depressive Episode
Location: Toronto, Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 18 - 65

Code: NCT04999553

Recruiting
Active & Responsive

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

for
Advanced Solid Tumors
Location: Moncton, Hackensack NJ, Fairfax VA, Kingston, Toronto,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05067283

Phase1, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase3, Recruiting
Active & Responsive

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: Providence RI, New York NY, Montreal, Chevy Chase MD,
Sponsor: Takeda

Sex: All

Age: 18 - 65

Code: NCT06095128

Recruiting
Active & Responsive

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for
Crohn's Disease
Location: Halifax, Providence RI, New York NY, Montreal,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT06233461

Phase2, Recruiting
Active & Responsive

Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation

for
Twin; Pregnancy, Affecting Fetus or Newborn,
Location: Boston MA, Toronto
Sponsor: Leiden University Medical Center

Sex: All

Age: 18 - 50

Code: NCT05952583

Recruiting
Active & Responsive

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for
Pleuropulmonary Blastoma
Location: Halifax, Boston MA, Quebec, Sherbrooke,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06647953

Phase3, Recruiting
Active & Responsive

A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1

for
Myotonic Dystrophy 1
Location: Chicoutimi, Montreal, Ottawa, Calgary
Sponsor: PepGen Inc

Sex: All

Age: 16 - 65

Code: NCT06667453

Phase2, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase2, Phase3, Recruiting
Active & Responsive

Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers

for
Adult Day Programs, Continuing Care, Old Age; Dementia,
Location: Multiple
Sponsor: York University

Sex: All

Age: 65+

Code: NCT06496945

Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Halifax, Boston MA, New York NY, Philadelphia PA,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for
Psoriatic Arthritis, Spondyloarthritis, Axial
Location: Quebec, Philadelphia PA, Ottawa, Cleveland OH,
Sponsor: CARE ARTHRITIS LTD.

Sex: All

Age: 18+

Code: NCT06454188

Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase1, Phase2, Recruiting

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