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Paid Clinical Trials Ontario

Discover 2,726 paid clinical trials in Ontario. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

for
Advanced Solid Tumors
Location: Moncton, Hackensack NJ, Fairfax VA, Kingston, Toronto,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05067283

Phase 1, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase 3, Recruiting
Active & Responsive

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: Providence RI, New York NY, Montreal, Chevy Chase MD,
Sponsor: Takeda

Sex: All

Age: 18 - 65

Code: NCT06095128

Recruiting
Active & Responsive

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for
Crohn's Disease
Location: London, Halifax, Providence RI, New York NY, Montreal,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT06233461

Phase 2, Recruiting
Active & Responsive

Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation

for
Twin; Pregnancy, Affecting Fetus or Newborn,
Location: Boston MA, Toronto
Sponsor: Leiden University Medical Center

Sex: All

Age: 18 - 50

Code: NCT05952583

Recruiting

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Active & Responsive

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for
Pleuropulmonary Blastoma
Location: Halifax, Boston MA, Quebec, Sherbrooke,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06647953

Phase 3, Recruiting
Active & Responsive

A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1

for
Myotonic Dystrophy 1
Location: Chicoutimi, Montreal, Ottawa, Calgary
Sponsor: PepGen Inc

Sex: All

Age: 16 - 65

Code: NCT06667453

Phase 2, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase 2, Phase 3, Recruiting
Active & Responsive

Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers

for
Adult Day Programs, Continuing Care, Old Age; Dementia,
Location: Multiple
Sponsor: York University

Sex: All

Age: 65+

Code: NCT06496945

Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Halifax, Boston MA, New York NY, Philadelphia PA,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for
Psoriatic Arthritis, Spondyloarthritis, Axial
Location: Quebec, Philadelphia PA, Ottawa, Cleveland OH,
Sponsor: CARE ARTHRITIS LTD.

Sex: All

Age: 18+

Code: NCT06454188

Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase 1, Phase 2, Recruiting
Active & Responsive

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for
Scoliosis Idiopathic
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Pediatric Spine Foundation

Sex: All

Age: 0 - 18

Code: NCT04914507

Recruiting
Active & Responsive

Axial Involvement in Psoriatic Arthritis Cohort

for
Psoriatic Arthritis
Location: Toronto
Sponsor: Charite University, Berlin, Germany

Sex: All

Age: 0+

Code: NCT04434885

Recruiting
Active & Responsive

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for
Non-small Cell Lung Cancer, NSCLC
Location: Hackensack NJ, Trois-Rivieres, Pennington NJ, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06422143

Phase 3, Recruiting
Active & Responsive

Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg Ulcers

for
Leg Ulcer
Location: Boston MA, Providence RI, Chapel Hill NC, Tamarac FL,
Sponsor: Intercytex

Sex: All

Age: 18+

Code: NCT00232973

Phase 3, Recruiting
New

Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial

for
Stroke, Ischemic
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 70+

Code: NCT07454707

Phase 3, Recruiting
New

A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers

for
Smoking Cessation, Nicotine Replacements Therapy
Location: Mississauga
Sponsor: McNeil AB

Sex: All

Age: 19 - 65

Code: NCT07893158

Phase 2, Recruiting
New

Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures

for
Traumatic Rib Fracture(s), Traumatic Rib Fracture
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07756047

Recruiting
New

Blood Transfusion Strategies During Major Surgery

for
Perioperative Red Blood Cell Transfusion
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT07748663

Recruiting

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