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Clinical Trials In Tennessee

Discover hundreds of clinical trials in Tennessee.
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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

Recruiting
PHASE2

Sponsor:

St. Jude Children's Research Hospital

Location:

Memphis

Code:

NCT06528691

Conditions

High Grade Glioma

CNS Tumor

Eligibility Criteria

Sex: All

Age: 0 - 3

Healthy Volunteers: Not accepted

Interventions

Entrectinib

Cyclophosphamide

Etoposide

Carboplatin

G-CSF

Safety and Efficacy of Talactoferrin in Addition to Standard Chemotherapy in Patients With Non-small Cell Lung Cancer

Recruiting
PHASE3

Sponsor:

Agennix

Location:

Nashville, Chattanooga, Chicago, Durhamshow 2 more

Code:

NCT00706862

Conditions

Non Small Cell Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Talactoferrin

Placebo

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Recruiting
PHASE3

Sponsor:

AstraZeneca

Location:

Nashville, Louisville, Germantown, Atlantashow 114 more

Code:

NCT06120491

Conditions

Metastatic Castration-Sensitive Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Saruparib

Placebo

Abiraterone Acetate

Darolutamide

Enzalutamide

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

Recruiting
PHASE3

Sponsor:

Hoffmann-La Roche

Location:

Nashville, Chattanooga, Knoxville, Alabastershow 43 more

Code:

NCT04873362

Conditions

Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Atezolizumab

Trastuzumab Emtansine

Placebo

Trastuzumab

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Recruiting
PHASE3

Sponsor:

Bellus Health Inc. - a GSK company

Location:

Jasper, Knoxville, Lawrenceville, Bristolshow 67 more

Code:

NCT05599191

Conditions

Refractory Chronic Cough

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

BLU-5937

Placebo

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

Recruiting
PHASE3

Sponsor:

Alexion Pharmaceuticals, Inc.

Location:

Knoxville, Acworth, Alabaster, Lawrencevilleshow 34 more

Code:

NCT06291376

Conditions

Immunoglobulin A Nephropathy

IgAN

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Ravulizumab

Placebo

10°C Vs 4°C Lung Preservation RCT

Recruiting

Sponsor:

University Health Network, Toronto

Location:

Nashville, Rochester, Toronto, San Francisco

Code:

NCT05898776

Conditions

Lung Transplant

Organ Preservation

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Lung transplantation after 10°C donor lung preservation

Lung transplantation after standard ice cooler donor lung preservation

Care Transitions in Renal Disease Patients

Recruiting

Sponsor:

Fresenius Medical Care North America

Location:

Franklin

Code:

NCT01842776

Conditions

Renal Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study of RYZ101 Compared with SOC in Pts W Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Recruiting
PHASE3

Sponsor:

RayzeBio, Inc.

Location:

Nashville, Atlanta, Lexington, St. Louisshow 28 more

Code:

NCT05477576

Conditions

GEP-NET

Gastroenteropancreatic Neuroendocrine Tumor

Gastroenteropancreatic Neuroendocrine Tumor Disease

Neuroendocrine Tumors

Carcinoid

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

RYZ101

Everolimus

Sunitinib

Octreotide

Lanreotide

Endovascular Therapy for Low NIHSS Ischemic Strokes

Recruiting
PHASE2
PHASE3

Sponsor:

Emory University

Location:

Atlanta, Memphis, Lexington, Bloomingtonshow 32 more

Code:

NCT04167527

Conditions

Cerebral Ischemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device

Initial medical management (iMM)

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