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Paid Clinical Trials Knoxville

Discover 211 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Knoxville TN, Nashville TN, Louisville KY, Newnan GA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for
Ovarian Cancer
Location: Knoxville TN, Lexington KY, Pinehurst NC, Hilliard OH,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT07059845

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, c-MET
Location: Knoxville TN, Nashville TN, Fort Wayne IN,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07155187

Phase2, Phase3, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Knoxville TN, Gainesville GA, Decatur GA, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for
Crohn's Disease, Ulcerative Colitis
Location: Knoxville TN, Asheville NC, Greenville SC, Roswell GA,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07697456

Phase2, Recruiting

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Featured

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: Knoxville TN, Bristol TN, Nashville TN, Louisville KY,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Knoxville TN, Johns Creek GA, Atlanta GA, Decatur GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting
Active & Responsive

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for
Pulmonary Hypertension, Interstitial Lung Disease (ILD)
Location: Knoxville TN, Lexington KY, Winston-Salem NC,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT06911632

Recruiting
Active & Responsive

AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

for
Feasibility Studies, Physical Activity,
Location: Knoxville TN
Sponsor: The University of Tennessee, Knoxville

Sex: All

Age: 65+

Code: NCT07768670

Recruiting
Active & Responsive

FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions

for
Acute Ischemic Stroke,
Location: Knoxville TN
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT07749170

Recruiting
Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Knoxville TN, Chattanooga TN, Nashville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase3, Recruiting
Active & Responsive

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

for
Clinical Stage 0 Cutaneous Melanoma AJCC v8,
Location: Knoxville TN, Memphis TN, Pittsburgh PA, Toledo OH,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT07621614

Phase2, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: Knoxville TN, Cleveland TN, Norcross GA,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for
Healthy
Location: Knoxville TN, Greer SC, Simpsonville SC, Cincinnati OH,
Sponsor: Pfizer

Sex: All

Age: 0 - 49

Code: NCT07160244

Phase3, Recruiting
Active & Responsive

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

for
Non-small Cell Lung Cancer
Location: Knoxville TN, Asheville NC, Chapel Hill NC, Raleigh NC,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07513376

Phase3, Recruiting
Active & Responsive

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer,
Location: Knoxville TN, Atlanta GA, Nashville TN, Edgewood KY,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT06901531

Phase3, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Knoxville TN, Spartanburg SC, Atlanta GA, Edgewood KY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase3, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

for
Menstrual Migraine
Location: Knoxville TN, Marietta GA, Stockbridge GA,
Sponsor: Pfizer

Sex: Female

Age: 18 - 45

Code: NCT06641466

Phase3, Recruiting
Active & Responsive

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for
Obesity, Overweight
Location: Nashville TN, Greenville SC, Dunwoody GA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07321886

Phase3, Recruiting
Active & ResponsiveNew

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

for
Overweight , Obesity, Adults
Location: Nashville TN, Birmingham AL, Wilmington NC,
Sponsor: Alveus Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07837973

Phase2, Recruiting