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A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

for
Advanced Malignant Solid Tumor, Solid Tumor Cancer
Location: Houston TX, Dallas TX, Los Angeles CA
Sponsor: Pilatus Biosciences Inc

Sex: All

Age: 18+

Code: NCT07337525

Phase1, Recruiting

TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

for
Advanced Malignant Solid Neoplasm,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT07189195

Phase1, Recruiting

Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia

for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT04984551

Phase2, Recruiting

Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors

for
Advanced Malignant Solid Neoplasm, Malignant Brain Neoplasm,
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 39

Code: NCT07174661

Recruiting

An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors

for
Advanced Malignant Solid Tumor
Location: Grand Rapids MI
Sponsor: Repertoire Immune Medicines

Sex: All

Age: 18+

Code: NCT07293754

Phase1, Phase2, Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for
Advanced Malignant Solid Neoplasm,
Location: Brewer ME, Augusta ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT05564377

Phase2, Recruiting

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

for
Advanced Malignant Solid Neoplasm,
Location: New Haven CT, Gainesville FL, Oklahoma City OK
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05053971

Phase1, Phase2, Recruiting

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

for
Advanced Malignant Solid Neoplasm,
Location: Columbus OH
Sponsor: Yuanquan Yang

Sex: All

Age: 18+

Code: NCT06470971

Phase2, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase1, Phase2, Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Providence RI, New York NY, Charleston SC,
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT04429542

Phase1, Recruiting

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult, Metastatic Breast Cancer,
Location: Boston MA, New York NY, Tampa FL, Indianapolis IN,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06625775

Phase1, Recruiting

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

for
Solid Tumor
Location: Providence RI, New York NY, Hackensack NJ, Newark DE,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT05584670

Phase1, Phase2, Recruiting

YL-13027 in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Houston TX
Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All

Age: 18+

Code: NCT05228600

Phase1, Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for
Lung Cancer, Breast Cancer
Location: Hackensack NJ, Montreal, Ottawa, Miami FL, Cleveland OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06618287

Phase1, Phase2, Recruiting

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for
Solid Tumors
Location: Fairfax VA, Grand Rapids MI, Minneapolis MN, Houston TX,
Sponsor: Adcentrx Therapeutics

Sex: All

Age: 18+

Code: NCT06710379

Phase1, Recruiting

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for
Solid Tumors, Hematologic Malignancies
Location: Nashville TN, Omaha NE, Houston TX, Duarte CA
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07195916

Phase1, Recruiting

Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors

for
Solid Tumor
Location: Philadelphia PA, Norfolk VA, Pittsburgh PA, Tampa FL,
Sponsor: ImmunoGenesis

Sex: All

Age: 18+

Code: NCT06014502

Phase1, Recruiting

A Study to Investigate CYC140, in Subjects With Advanced Solid Tumors and Lymphoma

for
Solid Tumor, Adult Lymphoma
Location: Pittsburgh PA, Houston TX, Duarte CA
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05358379

Phase1, Phase2, Recruiting

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

for
Neoplasms
Location: Boston MA, New Haven CT, Sherbrooke, New Brunswick NJ,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06551142

Phase1, Recruiting

A Study of PSB205 in Subjects With Advanced Solid Tumors

for
Neoplasm Malignant
Location: San Antonio TX
Sponsor: Qilu Puget Sound Biotherapeutics (dba Sound Biologics)

Sex: All

Age: 18+

Code: NCT03986606

Phase1, Recruiting