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A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for
Alzheimer Disease, Psychosis
Location: Independence OH, Gilbert AZ, Chino CA
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT06947941

Phase3, Recruiting

Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

for
Alzheimer Disease
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 60 - 70+

Code: NCT06801639

Recruiting

Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease

for
Alzheimer Disease, Healthy
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18 - 70+

Code: NCT05582200

Recruiting

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

for
Early Alzheimer's Disease
Location: Newton MA, New Haven CT, Queens NY, Toms River NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 50 - 70+

Code: NCT07033494

Phase2, Recruiting

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

for
Psychosis Associated With Alzheimer's Disease
Location: Levis, West Long Branch NJ, Boca Raton FL,
Sponsor: MapLight Therapeutics

Sex: All

Age: 55 - 70+

Code: NCT06887192

Phase2, Recruiting

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Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease

for
Alzheimer Disease
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 50+

Code: NCT04576793

Phase2, Recruiting

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease

for
Alzheimer Disease, Chronic Traumatic Encephalopathy
Location: Evanston IL
Sponsor: CereMark Pharma, LLC

Sex: All

Age: 45+

Code: NCT06254469

Phase3, Recruiting

Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers

for
Mild Cognitive Impairment, Alzheimer Disease, Dementia
Location: Greenfield Park
Sponsor: MoCA Clinic and Institute

Sex: All

Age: 55 - 70+

Code: NCT07041450

Recruiting

Olfactory Biopsies

for
Alzheimer Disease, Smell Loss, Smell Dysfunction
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07021040

Recruiting

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

for
Alzheimer Disease and Related Dementias (ADRD),
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 50+

Code: NCT07120347

Recruiting

Speech Pattern Evaluation and Analysis for Knowledge of AD

for
Wisconsin Alzheimer's Disease Research Center,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 40 - 70+

Code: NCT06230783

Recruiting

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

for
Alzheimer Disease, Mild Cognitive Impairment
Location: Charlestown MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 50 - 70+

Code: NCT05904132

Recruiting

Dementia Caregivers' Link to Assistance and Resources

for
Alzheimer Disease or Associated Disorder, Dementia
Location: New York NY
Sponsor: Visiting Nurse Service of New York

Sex: All

Age: 0+

Code: NCT06860035

Recruiting

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

for
Alzheimer's Disease
Location: West Long Branch NJ, Albany NY, Springfield NJ,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976203

Phase3, Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for
Agitation, Alzheimer Disease
Location: Foxborough MA, Manhasset NY, New Windsor NY,
Sponsor: Celgene

Sex: All

Age: 55 - 70+

Code: NCT06808984

Phase2, Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

for
Alzheimer's Disease
Location: Valley Stream NY, Staten Island NY, Morehead City NC,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT07011745

Phase3, Recruiting

Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia,
Location: Englewood NJ
Sponsor: Akiva Mintz

Sex: All

Age: 18 - 70+

Code: NCT07012993

Phase2, Recruiting

Mindfulness to Enhance Cognitive Health in Latino Older Adults

for
Mindfulness, Alzheimer's Disease Related Dementia
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 65+

Code: NCT07040904

Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for
Alzheimer Disease
Location: South Dartmouth MA, Newton MA, Springfield MA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT07011732

Phase3, Recruiting

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease

for
Alzheimer&Amp;#39;s Disease-related Dementia, Alzheimer Disease,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 65 - 70+

Code: NCT06835283

Recruiting