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Combined Immunotherapies in Metastatic ER+ Breast Cancer

for
Breast Cancer
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 70+

Code: NCT04563507

Phase2, Recruiting

Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer

for
Breast Cancer, Brain Metastases
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18+

Code: NCT06072807

Recruiting

Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer

for
HER2-positive Breast Cancer, Advanced Breast Cancer
Location: Boston MA, Miami FL
Sponsor: University of Miami

Sex: Female

Age: 18+

Code: NCT06123988

Recruiting

MATCH-UP: MAking Telehealth-Delivery of Cancer Care at Home Effective and Safe-Upscaled: A Pragmatic Cluster Randomized Trial

for
Breast Cancer, Prostate Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06954337

Recruiting

CtDNA Based MRD Testing for NAC Monitoring in TNBC

for
TNBC - Triple-Negative Breast Cancer, Minimal Residual Disease
Location: Stony Brook NY, York PA, Washington DC DC,
Sponsor: Personalis Inc.

Sex: Female

Age: 18+

Code: NCT06230185

Recruiting

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Cardio-Oncology Rehabilitation Exercise

for
Breast Cancer
Location: Toronto
Sponsor: University of Toronto

Sex: Female

Age: 18+

Code: NCT05522959

Recruiting

Core Biopsies for Establishing a Breast Tumor Tissue Repository

for
Breast Cancer
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT02250352

Recruiting

TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery

for
Breast Adenocarcinoma, Stage II Breast Cancer AJCC v6 and v7,
Location: Lebanon NH, Pinehurst NC, Jacksonville FL,
Sponsor: Academic and Community Cancer Research United

Sex: Female

Age: 18+

Code: NCT04197687

Phase2, Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

for
Breast Cancer
Location: Fairfax VA, Rochester MN, Omaha NE, Houston TX,
Sponsor: Biotheryx, Inc.

Sex: All

Age: 18+

Code: NCT06515470

Phase1, Recruiting

Cryoablation vs Lumpectomy in T1 Breast Cancers

for
Breast Cancer, Breast Neoplasm
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: Female

Age: 50+

Code: NCT05505643

Recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer

for
Breast Cancer, HER2-positive Breast Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06441890

Phase2, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Providence RI, New Haven CT, Quebec, Stony Brook NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

for
Locally Advanced Breast Cancer, Unresectable Breast Carcinoma,
Location: New York NY, Stony Brook NY, Chicoutimi, Uniondale NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06827236

Phase1, Phase2, Recruiting

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

for
Breast Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06247449

Recruiting

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

for
Early Breast Cancer
Location: Boston MA, Providence RI, Lake Success NY, Jamaica NY,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05827081

Phase3, Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting

5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer

for
Breast Cancer, Invasive Carcinoma of Breast,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Female

Age: 18+

Code: NCT06961955

Phase2, Recruiting

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for
Breast Cancer, Metastatic Breast Cancer, Breast Neoplasm,
Location: Riverhead NY, Patchogue NY, Port Jefferson Station NY,
Sponsor: BriaCell Therapeutics Corporation

Sex: All

Age: 18+

Code: NCT06072612

Phase3, Recruiting

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Columbus OH, Grand Rapids MI, Houston TX,
Sponsor: Tanabe Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT06943521

Phase1, Phase2, Recruiting

Genomic Investigation of Unusual Responders

for
Cancer, Breast Cancer, Non-small Cell Lung Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03740503

Recruiting