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A Split-Mouth Clinical Trial Evaluating the Bond Failure Rate of a New Etch-Free Orthodontic Adhesive

for
Bracket Bonding, Orthodontic Treatment,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 14 - 35

Code: NCT07091422

Recruiting

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

for
Mantle Cell Lymphoma
Location: Toronto, Vancouver
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT07341191

Phase2, Recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

for
Non Small Cell Lung Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06364917

Phase2, Recruiting

Aromatherapy Inhaler Use for HSCT Distress

for
Cancer Distress, Cancer Coping,
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT05302583

Recruiting

Pharmacogenomics-Supported Psychotropic Prescribing Trial

for
Mental Disorder, Pharmacogenetics, Adverse Drug Reaction (ADR),
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT06929533

Recruiting

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Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

for
Neurofibromatosis Type 2, Vestibular Schwannoma,
Location: Boston MA, New York NY, Baltimore MD, Miami FL,
Sponsor: Scott R. Plotkin, MD, PhD

Sex: All

Age: 12+

Code: NCT04374305

Phase2, Recruiting

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

for
Generalized Anxiety Disorder (GAD)
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07430800

Recruiting

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

for
Dementia, Potentially Inappropriate Medication Use,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 65+

Code: NCT07454824

Recruiting

A Multi-center, Early Feasibility Study of Using the Mechanical Tissue Resuscitation™ (MTR®) Therapy System for Removal of Excess Fluid in Subjects Who Have Had a Portion of Their Skull Removed to Expose the Dura/Brain and Require Drainage for Fluid Removal.

for
Clinical Need for Craniotomy or Craniectomy,
Location: Buffalo NY, Winston-Salem NC, Morgantown WV
Sponsor: Renovo Concepts, Inc.

Sex: All

Age: 22 - 65

Code: NCT06201429

Recruiting

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

for
Treatment Resistant Depression (TRD)
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07563868

Recruiting

Recovering Sleep After Trauma

for
Post-traumatic Stress Disorder
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 65

Code: NCT07196332

Recruiting

DIALysis With EXpanded Solute Removal

for
Chronic Kidney Disease Requiring Hemodialysis,
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 45+

Code: NCT06660277

Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

for
Relapsed AL Amyloidosis, Refractory AL Amyloidosis,
Location: Boston MA, New York NY, Toronto, Tampa FL, Cleveland OH,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07081646

Phase1, Phase2, Recruiting

Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

for
Post-bariatric Surgery
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18 - 65

Code: NCT01803451

Early_phase1, Recruiting

Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk

for
HER2-Positive Breast Carcinoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 0+

Code: NCT06557057

Recruiting

Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases

for
Brain (Nervous System) Cancers, Brain Metastasases, SRS
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07162246

Phase2, Recruiting

SMART Therapist Training: A Hybrid Factorial-SMART Design

for
Stress Disorders, Post-Traumatic, Psychotherapy
Location: Ann Arbor MI, Cincinnati OH, Minneapolis MN,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT07010770

Recruiting

Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

for
Longevity, GLP-1, Geroscience, Aging
Location: Chicago IL
Sponsor: AgelessRx

Sex: All

Age: 40 - 70+

Code: NCT07092618

Phase2, Phase3, Recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for
ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Lake Success NY, East Brunswick NJ, Fairfax VA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18 - 70+

Code: NCT07540572

Phase1, Recruiting

Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

for
Diabetes Mellitus, Type 2, Diabetes, Type 2 Diabetes,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 30 - 70

Code: NCT06657209

Recruiting