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Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

for
Post-Traumatic Stress Disorder (PTSD)
Location: San Diego CA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06194851

Phase2, Recruiting

Irrisept Solution for Instrumented Spine Surgery

for
Post-Op Complication, Spine Surgery, Site Infection,
Location: Providence RI
Sponsor: Rhode Island Hospital

Sex: All

Age: 18+

Code: NCT06439953

Recruiting

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

for
Psychotic Disorders, Alzheimer Disease
Location: Toms River NJ, Miami FL, Doral FL, Homestead FL,
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 55+

Code: NCT06540833

Phase2, Recruiting

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for
Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer,
Location: Boston MA, New York NY, Fairfax VA, Pittsburgh PA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06128551

Phase1, Phase2, Recruiting

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

for
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance),
Location: Atlanta GA
Sponsor: Georgia State University

Sex: Female

Age: 20 - 65

Code: NCT06735651

Recruiting

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Evaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training Program

for
Tics, Tic Disorders, Tourette Syndrome
Location: Milwaukee WI, Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 7+

Code: NCT05547854

Recruiting

The Minimalist Trial-2

for
HPV-Related Oropharynx Squamous Cell Carcinoma
Location: St Louis MO, Fargo ND, Sioux Falls SD
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06702033

Phase2, Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: The Bronx NY, Newark NJ, New Brunswick NJ, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05172245

Phase1, Recruiting

Peanuts for Cardiometabolic, Brain, and Intestinal Health

for
Prediabetes,
Location: Atlanta GA
Sponsor: Georgia State University

Sex: All

Age: 20 - 59

Code: NCT06867198

Recruiting

PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose

for
Acute Post Operative Pain, Laparotomy, Epidural Analgesia
Location: Montreal
Sponsor: Ciusss de L'Est de l'Île de Montréal

Sex: All

Age: 18 - 70+

Code: NCT05534945

Recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

for
Somatostatin Receptor Positive,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06427798

Phase1, Phase2, Recruiting

The ReTAVI Prospective Observational Registry

for
Structural Valve Deterioration, Structural Valve Degeneration,
Location: Quebec, Montreal, Vancouver
Sponsor: Institut für Pharmakologie und Präventive Medizin

Sex: All

Age: 18+

Code: NCT05601453

Recruiting

A Prospective Registry of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS).

for
Hematopoietic Cell Transplantation
Location: Durham NC, Rochester MN, Houston TX
Sponsor: Duke University

Sex: All

Age: 0 - 26

Code: NCT05090345

Recruiting

A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation

for
KRAS P.G12C
Location: Sarasota FL, Detroit MI, Nashville TN, Houston TX,
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT05410145

Phase1, Phase2, Recruiting

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

for
Anal Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06050707

Phase2, Recruiting

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

for
Glioma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT01772771

Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Halifax, Worcester MA, Montreal, Media PA, Newark DE,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT05920356

Phase3, Recruiting

Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

for
Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT04974671

Phase2, Recruiting

PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

for
End Stage Renal Disease, Hemodialysis Access Failure
Location: Norfolk VA, Washington D.C. DC, Raleigh NC,
Sponsor: Merit Medical Systems, Inc.

Sex: All

Age: 18+

Code: NCT06422871

Recruiting

A Study of Radiation Therapy After Surgery in People With Oral Tongue Squamous Cell Carcinoma

for
Oral Tongue Squamous Cell Carcinoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06485778

Phase2, Recruiting