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Concurrent Neoadjuvant Chemo/Endocrine Therapy in HER2+ Breast Cancer

for
Breast Cancer - Infiltrating Ductal Carcinoma,
Location: Gresham OR, Vancouver WA, Portland OR, Tualatin OR
Sponsor: Legacy Health System

Sex: All

Age: 18+

Code: NCT07506876

Phase2, Recruiting

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

for
Head and Neck Cancer,
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 18+

Code: NCT07213934

Phase1, Phase2, Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06910761

Phase2, Recruiting

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for
AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL),
Location: Boston MA, New York NY, Charlottesville VA,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 18 - 66

Code: NCT06859424

Phase2, Recruiting

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Toripalimab With Chemotherapy for Sinus Cancer

for
Sinonasal Cancer, Paranasal Sinus Neoplasms,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06940180

Phase2, Recruiting

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693377

Recruiting

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

for
Stage III Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04892953

Phase2, Recruiting

Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06260033

Phase2, Recruiting

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for
Hodgkin Lymphoma in Remission, Leukemia in Remission,
Location: Scarborough ME, Boston MA, Providence RI, New Haven CT,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT01790152

Recruiting

Safety and Efficacy of PMT Therapy of hPAP

for
Hereditary Pulmonary Alveolar Proteinosis
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 18+

Code: NCT05761899

Phase1, Phase2, Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for
Central Nervous System Nongerminomatous Germ Cell Tumor,
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT04684368

Phase2, Recruiting

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Portland ME, Scarborough ME, Sanford ME, Stony Brook NY,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500455

Phase3, Recruiting

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

for
Breast Cancer, Axillary Nodal Disease, Female Breast Cancer,
Location: Pasadena CA, Los Angeles CA, Tarzana CA
Sponsor: Alice Chung

Sex: Female

Age: 45+

Code: NCT06092892

Phase2, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase1, Phase2, Recruiting

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

for
Hematologic Malignancy, Solid Tumor, Sickle Cell Disease,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 8+

Code: NCT06689800

Recruiting

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

for
Oligometastatic Breast Carcinoma, Breast Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05534438

Phase2, Recruiting

De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You

for
Breast Cancer
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 70+

Code: NCT05134779

Recruiting

CONFIRM: Magnetic Resonance Guided Radiation Therapy

for
Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT04368702

Recruiting

The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients with Biochemical Failure Status Post Salvage or Radical Radiation Therapy

for
Prostate Cancer
Location: Quebec, Chicoutimi, Trois-Rivieres, Greenfield Park,
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: Male

Age: 18+

Code: NCT02573636

Recruiting