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A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

for
Glioblastoma Multiforme of Brain, Glioma, Glioblastoma
Location: New York NY, Tampa FL, Chicago IL
Sponsor: Tetragon Biosciences Ltd

Sex: All

Age: 18+

Code: NCT07464925

Phase1, Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

G-CSF After Chemo-radiation in Patients With Glioblastoma

for
MGMT-Methylated Glioblastoma, Glioblastoma (GBM),
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06649851

Phase2, Recruiting

Tamoxifen Versus Etoposide After First Recurrence in GBM Patients

for
Glioblastoma Multiforme
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18 - 65

Code: NCT04765098

Phase2, Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

for
Malignant Glioma of Brain, Astrocytoma, Malignant Astrocytoma,
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT05686798

Phase1, Recruiting

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Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma

for
Glioblastoma Multiforme, Relapse
Location: Sherbrooke
Sponsor: Université de Sherbrooke

Sex: All

Age: 18+

Code: NCT06356883

Phase2, Recruiting

AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Durham NC, Detroit MI, Chicago IL, Dallas TX,
Sponsor: Novacea

Sex: All

Age: 18+

Code: NCT00394628

Phase1, Phase2, Recruiting

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

for
Glioblastoma Multiforme, Anaplastic Astrocytoma
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT01269853

Phase1, Phase2, Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Washington D.C. DC, Durham NC, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 39

Code: NCT05843253

Phase2, Recruiting

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

for
Glioblastoma Multiforme
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT05083754

Phase1, Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

for
Neoplasms, Brain, Glioblastoma Multiforme,
Location: Birmingham AL, St Louis MO, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 3 - 22

Code: NCT03911388

Phase1, Recruiting

Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab

for
Glioma, Glioblastoma Multiforme
Location: Rochester MN, Omaha NE
Sponsor: Aveta Biomics, Inc.

Sex: All

Age: 19+

Code: NCT06011109

Phase1, Phase2, Recruiting

Sonodynamic Therapy in Patients With Recurrent GBM

for
Recurrent Glioblastoma, Glioblastoma Multiforme, GBM
Location: Charlottesville VA
Sponsor: Shayan Moosa, MD

Sex: All

Age: 18 - 70+

Code: NCT06039709

Phase1, Recruiting

Loupe-Based Intraoperative Fluorescence Imaging

for
Glioblastoma Multiforme, Anaplastic Astrocytoma
Location: Lexington KY
Sponsor: Guoqiang Yu

Sex: All

Age: 18 - 70+

Code: NCT04780009

Recruiting

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

for
Glioblastoma, Recurrent Glioblastoma,
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06613841

Early_phase1, Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Montreal, Hershey PA, Chapel Hill NC, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase2, Recruiting

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

for
Glioblastoma Multiforme, Recurrent Glioblastoma
Location: New York NY, Jacksonville FL, Chicago IL, St Louis MO,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT05303467

Phase1, Recruiting

Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

for
Glioblastoma Multiforme
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05864976

Recruiting
New

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: The Bronx NY, New York NY, Bel Air MD, Glen Burnie MD,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase3, Recruiting
New

Assessing Brain Metabolism Using MRS With Deuterated Glucose

for
Glioma
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06594315

Recruiting