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Active & Responsive

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

for
Cystic Fibrosis (CF), New Diagnostics
Location: Philadelphia PA, Pittsburgh PA, Milwaukee WI,
Sponsor: Chris Goss

Sex: All

Age: 16+

Code: NCT07312734

Recruiting
Active & Responsive

Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation

for
Right Heart Failure, Right Ventricular Dysfunction
Location: Montreal
Sponsor: Montreal Heart Institute

Sex: All

Age: 18+

Code: NCT05450328

Phase2, Recruiting
Active & Responsive

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

for
Endometrial Cancer, Ovarian Cancer, Ovarian Cancer Metastatic,
Location: Hackensack NJ, Fairfax VA, Buffalo NY, Cleveland OH,
Sponsor: Whitehawk Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07444814

Phase1, Recruiting
Active & Responsive

DBC-664 in Adult Patients With Solid Tumors

for
Malignant Germ Cell Tumor, Lung Adenocarcinoma,
Location: Lake Success NY, East Brunswick NJ, Grand Rapids MI,
Sponsor: Duboce Biopharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07705035

Phase1, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Huntersville NC,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting

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Active & Responsive

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: New York NY, Belleville NJ, Philadelphia PA, Newark DE,
Sponsor: Immuneering Corporation

Sex: All

Age: 18+

Code: NCT07562152

Phase3, Recruiting
Active & ResponsiveNew

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Tampa FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07805954

Phase3, Recruiting
Active & Responsive

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT07428707

Early_phase1, Recruiting
Active & Responsive

ACT Lung Health Intervention: Phase Two

for
Smoking Cessation, Smoking Behaviors, Smoking, Tobacco,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT06945120

Recruiting
New

SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier

for
Lung Cancer, Lung Nodule
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 21+

Code: NCT07460440

Recruiting
New

Study of NXP900 With Lorlatinib in ALK+ Lung Cancer

for
ALK Positive, ALK Positive Non-small Cell Lung Cancer, NSCLC,
Location: Fairfax VA
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 0+

Code: NCT07784959

Phase1, Recruiting
New

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

for
Family History of Lung Cancer
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07600801

Recruiting
New

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07322341

Phase2, Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting
New

Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC

for
NSCLC, Non-small Cell Lung Cancer,
Location: Plantation FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07777822

Phase3, Recruiting
New

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

for
Advanced Colorectal Carcinoma,
Location: Pleasanton CA
Sponsor: Kaiser Permanente

Sex: All

Age: 18+

Code: NCT07776353

Recruiting
New

Pemefolacianine for IMI of Lung Cancer

for
Lung Cancer (Locally Advanced or Metastatic)
Location: Philadelphia PA
Sponsor: Sunil Singhal

Sex: All

Age: 18+

Code: NCT07772895

Phase1, Recruiting
New

Evaluating the Impact of CONNECT in a Multilingual Population

for
Smoking Cessation,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 50 - 70+

Code: NCT07111936

Recruiting
New

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Cardiotoxicity,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07761910

Phase2, Recruiting
New

A Study of Armored CAR T Cells in People With Cancer

for
Neuroendocrine Cancer, Small Cell Lung Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07783477

Phase1, Recruiting