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Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for
Atrial Fibrillation (AF)
Location: Valhalla NY, Philadelphia PA, Jacksonville FL, Tampa FL,
Sponsor: Vektor Medical

Sex: All

Age: 22+

Code: NCT06935591

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

for
Lung Transplant Infection, Heart Transplant Infection,
Location: Toronto
Sponsor: Jordan Feld

Sex: All

Age: 0+

Code: NCT04017338

Phase3, Recruiting

Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas

for
Empyema, Pleural, Pleural Infection
Location: New York NY, Richmond VA, Sterling Heights MI,
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18+

Code: NCT06427538

Recruiting

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

for
Mesothelioma, Neoplasms, Stomach Neoplasms,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06885697

Phase1, Recruiting

Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema

for
Emphysema or COPD
Location: Boston MA
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 40 - 70+

Code: NCT04801108

Recruiting

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Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

for
Acute Respiratory Distress Syndrome,
Location: Hyattsville MD, Columbus OH, Detroit MI, Denver CO,
Sponsor: Vasomune Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05123755

Phase2, Recruiting

Oral Supplementation During PR Participation in COPD

for
Copd
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 40+

Code: NCT06324214

Phase2, Recruiting

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

for
Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD,
Location: Detroit MI
Sponsor: VA Office of Research and Development

Sex: All

Age: 60+

Code: NCT04179981

Recruiting

A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

for
Mechanical Ventilation Complication,
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT03405779

Recruiting

Kingston Chronic Obstructive Pulmonary Disease (COPD) Multidimensional Long Term Follow up Cohort

for
COPD, Emphysema
Location: Kingston
Sponsor: Dr. Juan Pablo de Torres Tajes

Sex: All

Age: 40 - 70+

Code: NCT04200079

Recruiting

Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking

for
Cannabis Use, Cannabis Smoking, Marijuana Smoking,
Location: London
Sponsor: Western University, Canada

Sex: All

Age: 18 - 70+

Code: NCT03909477

Recruiting

Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

for
Thoracic, Surgery, Mechanical Ventilation, Hypercapnia,
Location: Quebec
Sponsor: Laval University

Sex: All

Age: 18+

Code: NCT07099963

Recruiting

Improving CPR Quality With Longitudinal Practice and Realtime Feedback - RCT With CEA

for
Cardiopulmonary Resuscitation
Location: Calgary
Sponsor: Alberta Children's Hospital

Sex: All

Age: 18+

Code: NCT02539238

Recruiting

Using Xe MRI to Guide Radiation Therapy for Lung Cancer

for
Imaging Techniques
Location: Iowa City IA
Sponsor: Sean Fain

Sex: All

Age: 18 - 70+

Code: NCT06925295

Phase2, Recruiting

Lung Injury is One of the Primary Causes of Morbidity and Mortality in Critically Ill Patients. These Patients Will be Monitored for: 1) Immune Cell Activation 2) Blood-based Biomarkers. In Vitro Models Derived From These Samples Will be Treated With Novel Agent PIP-2 to Evaluate Its Efficacy.

for
ARDS (Acute Respiratory Distress Syndrome)
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 21 - 70+

Code: NCT07125079

Recruiting
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A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Squamous Non-Small Cell Lung Cancer
Location: Ottawa, Fairfax VA, Orange City FL, Houston TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07005102

Phase2, Phase3, Recruiting

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for
Ischemic Heart Disease (IHD),
Location: Boston MA, Roslyn NY, Richmond VA, Charlottesville VA,
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 35 - 70+

Code: NCT06854458

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

for
Community-acquired Pneumonia
Location: New York NY, Winston-Salem NC, Houston TX,
Sponsor: Biotest

Sex: All

Age: 18+

Code: NCT05722938

Phase3, Recruiting

Biomarkers of Phage Treatment Response in NTM and Other Infections

for
Nontuberculous Mycobacterial Lung Disease
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07076238

Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

for
Systemic Sclerosis Associated Interstitial Lung Disease,
Location: New York NY, Philadelphia PA, Baltimore MD,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT05878717

Phase2, Phase3, Recruiting