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PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

for
Glioma, Medulloblastoma, Ependymoma, Glioblastoma
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161519

Phase1, Phase2, Recruiting

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

for
Glioblastoma, WHO Grade II Glioma, WHO Grade III Glioma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04479696

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

for
Glioblastoma, High-grade Glioma, Glioblastoma, IDH-wildtype,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06118723

Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

for
Central Nervous System Neoplasms, Glioblastoma,
Location: Bethesda MD
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04541082

Phase1, Recruiting

Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®

for
Glioblastoma Multiforme of Brain, Glioma, Sarcomatous
Location: Buffalo NY
Sponsor: Photolitec LLC

Sex: All

Age: 18+

Code: NCT05363826

Phase1, Recruiting

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Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

for
Glioblastoma, Anaplastic Astrocytoma,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT02800486

Phase2, Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Miami FL
Sponsor: Florida International University

Sex: All

Age: 0 - 21

Code: NCT05857969

Phase1, Recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

for
WHO Grade 3 Glioma, WHO Grade 4 Glioma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06444412

Phase2, Recruiting

Development of MRF for Characterization of Brain Tumors After Radiotherapy

for
Brain Tumor, Brain Necrosis, Brain Metastases, Glioma
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18 - 60

Code: NCT06101069

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

for
Advanced Malignant Solid Neoplasm, RAS Mutation, Lung Cancer,
Location: Nashville TN, Denver CO, Los Angeles CA
Sponsor: RasCal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04678648

Phase1, Recruiting

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

for
Astrocytoma, Glioma, Recurrent Glioblastoma
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06344130

Phase1, Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

for
Anaplastic Astrocytoma, IDH-Wildtype,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04623931

Phase2, Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

for
Glioblastoma, Glioblastoma Multiforme,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06283927

Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

F-Tryptophan PET/CT in Human Cancers

for
Intracranial Glioma, Metastatic Brain Tumor, Breast Cancer,
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT05556473

Phase1, Recruiting

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

for
Glioma, Glioblastoma, Brain Tumor
Location: Bel Air MD, Glen Burnie MD, Baltimore MD, Columbia MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT04699773

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

for
Glioblastoma, IDH-wildtype, Glioblastoma,
Location: Boston MA, San Francisco CA
Sponsor: Erasmus Medical Center

Sex: All

Age: 0 - 70+

Code: NCT06273176

Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for
Diffuse Intrinsic Pontine Glioma, DIPG, Brain Tumor, CNS Tumor,
Location: Seattle WA
Sponsor: BrainChild Bio, Inc

Sex: All

Age: 1 - 26

Code: NCT07680439

Phase2, Recruiting

Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8, Glioblastoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07664579

Recruiting