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ASCENT Intervention for Brain Tumor Patients

for
Malignant Brain Tumor, Glioma, Coping Skills,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06099743

Recruiting

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

for
Low-grade Glioma, Recurrent Low Grade Glioma,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 2 - 25

Code: NCT07506239

Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

for
Glioblastoma, Brain Cancer, Brain Neoplasm, Brain Tumor,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT02861898

Phase1, Phase2, Recruiting

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

for
Glioma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT01772771

Recruiting

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HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

for
Neoplasms, Brain, Glioblastoma Multiforme,
Location: Birmingham AL, St Louis MO, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 3 - 22

Code: NCT03911388

Phase1, Recruiting

Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab

for
Glioma, Glioblastoma Multiforme
Location: Rochester MN, Omaha NE
Sponsor: Aveta Biomics, Inc.

Sex: All

Age: 19+

Code: NCT06011109

Phase1, Phase2, Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase3, Recruiting

Implantable Microdevice In Primary Brain Tumors

for
Grade II Glioma, Grade III Glioma, Grade IV Glioma, Astrocytoma,
Location: Boston MA
Sponsor: Oliver Jonas

Sex: All

Age: 18+

Code: NCT04135807

Early_phase1, Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

for
Primary Brain Tumor, Glioma, Meningioma, Schwannoma
Location: San Diego CA
Sponsor: Jona Hattangadi-Gluth

Sex: All

Age: 18 - 70+

Code: NCT05576103

Recruiting
New

Vorasidenib Maintenance for IDH Mutant Astrocytoma

for
IDH-mutant Grade 2 or 3 Astrocytoma
Location: Winnipeg
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT06809322

Phase3, Recruiting
New

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: The Bronx NY, New York NY, Bel Air MD, Glen Burnie MD,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase3, Recruiting
New

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

for
Phase 1, NK Cell, IL13Ra, EGFRvIII,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07579208

Phase1, Recruiting
New

Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma

for
Glioblastoma, IDH-Wildtype
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07708961

Phase2, Recruiting

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

for
Glioblastoma, Glioblastoma Multiforme, Gliosarcoma
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05756985

Recruiting

Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

for
Glioblastoma Multiforme
Location: Montreal, Calgary
Sponsor: Bassam Abdulkarim

Sex: All

Age: 18 - 70

Code: NCT02928575

Phase2, Recruiting

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

for
Glioblastoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06672575

Phase1, Phase2, Recruiting

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

for
Glioblastoma Multiforme
Location: Durham NC, Los Angeles CA, Santa Monica CA,
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT05708352

Phase2, Recruiting

Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

for
Pediatric Retinoblastoma, Retinoblastoma
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 6 - 17

Code: NCT03546387

Recruiting

FDG and FDOPA PET Demonstration of Functional Brain Abnormalities

for
Glioblastoma
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT04315584

Early_phase1, Recruiting