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Family Communications After Genetic Testing

for
Colon Adenocarcinoma, Colorectal Adenocarcinoma,
Location: Meadowbrook PA, East Stroudsburg PA, Bethlehem PA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07143487

Recruiting

Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

for
Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07128355

Early_phase1, Recruiting

Remote Monitoring and Symptom Management Digital Application

for
Breast Cancer (Locally Advanced or Metastatic), Lymphoma,
Location: Boston MA
Sponsor: Patrick C. Johnson, MD

Sex: All

Age: 18+

Code: NCT07553572

Recruiting

Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")

for
Colorectal Cancer, Peritoneal Metastases, Carcinomatosis
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07411599

Phase1, Phase2, Recruiting

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

for
Esophageal Squamous Cell Carcinoma,
Location: Lake Success NY, Fairfax VA, Sarasota FL, Detroit MI,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07503808

Phase1, Recruiting

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Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

for
Metastatic Colorectal Carcinoma (mCRC), Colorectal Cancer (CRC),
Location: Scottsdale AZ
Sponsor: HonorHealth Research Institute

Sex: All

Age: 18+

Code: NCT07463599

Phase1, Phase2, Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for
Renal Cell Carcinoma (RCC),
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05176483

Phase1, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

for
Advanced Breast Cancer, Metastatic Breast Cancer (HR+/ HER2-),
Location: New York NY, Long Island City NY, Grand Rapids MI,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07318805

Phase1, Recruiting

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

for
Head and Neck Squamous Cell Carcinoma HNSCC,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Sutro Biopharma, Inc.

Sex: All

Age: 18+

Code: NCT07227168

Phase1, Recruiting

Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases

for
Colorectal Cancer Liver Metastases (CRLM),
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07224724

Recruiting

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

for
Breast Cancer, Prostate Cancer, Colorectal Cancer,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07225309

Recruiting

Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma

for
Colorectal Adenocarcinoma Metastatic in the Liver
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT07082439

Phase2, Recruiting

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

for
Cervical Squamous Cell Carcinoma,
Location: New Haven CT, Hackensack NJ, Fairfax VA, Louisville KY,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT07169734

Phase1, Phase2, Recruiting

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

for
Locally Advanced Colorectal Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06307548

Phase1, Phase2, Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Raleigh NC, Tampa FL, Detroit MI, St Louis MO,
Sponsor: MOMA Therapeutics

Sex: All

Age: 18+

Code: NCT06974110

Phase1, Recruiting

Intravital Microscopy in Human Solid Tumors

for
Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03823144

Recruiting

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

for
Colorectal Cancer, Liver Metastases, Liver Cancer
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07044362

Recruiting

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

for
Vulvar Adenocarcinoma, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Fairfax VA, Grand Rapids MI, Irving TX
Sponsor: Avacta Life Sciences Ltd

Sex: All

Age: 18+

Code: NCT07454642

Phase1, Recruiting

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693377

Recruiting