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Active & Responsive

Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

for
Parkinson Disease
Location: Ann Arbor MI
Sponsor: University of Michigan

Sex: All

Age: 45+

Code: NCT07642908

Recruiting
Active & Responsive

Adapting rHIRE and Sleep Monitoring in Parkinson's Disease

for
PARKINSON DISEASE (Disorder)
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT07498296

Recruiting
Active & Responsive

Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease

for
PARKINSON DISEASE (Disorder)
Location: Montreal
Sponsor: McGill University

Sex: All

Age: 50+

Code: NCT07351032

Recruiting
Active & Responsive

tDCS as Treatment for Motor Function

for
Progressive Supranuclear Palsy,
Location: Toronto
Sponsor: Baycrest

Sex: All

Age: 0+

Code: NCT07291687

Recruiting
Active & Responsive

Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder

for
PARKINSON DISEASE (Disorder), Parkinson, Parkinson s Disease,
Location: Branford CT
Sponsor: CND Life Sciences

Sex: All

Age: 40 - 70+

Code: NCT07217054

Recruiting

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Active & Responsive

Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

for
PARKINSON DISEASE (Disorder), Parkinson,
Location: Portland OR
Sponsor: CND Life Sciences

Sex: All

Age: 40 - 70+

Code: NCT07204652

Recruiting
Active & Responsive

Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

for
Parkinson Disease, Parkinsonism
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 40 - 70+

Code: NCT07674264

Recruiting
Active & Responsive

A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery

for
Parkinson's Disease
Location: Lexington KY
Sponsor: Craig van Horne, MD, PhD

Sex: All

Age: 45 - 70+

Code: NCT06683378

Phase1, Recruiting
Active & Responsive

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

for
PARKINSON DISEASE (Disorder), Advanced Parkinson's Disease
Location: Hallandale FL, Maitland FL, Farmington Hills MI
Sponsor: Serina Therapeutics

Sex: All

Age: 40 - 70+

Code: NCT07422675

Phase1, Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for
Parkinson Disease
Location: Boston MA, New York NY, Durham NC, Boca Raton FL,
Sponsor: Appello Pharmaceuticals, Inc.

Sex: All

Age: 30 - 70+

Code: NCT07432958

Phase2, Recruiting
Active & Responsive

This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease.

for
Parkinson Disease
Location: New York NY
Sponsor: iRegene Therapeutics Co., Ltd.

Sex: All

Age: 30 - 70+

Code: NCT07102342

Phase1, Phase2, Recruiting
Active & Responsive

Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

for
Parkinson Disease
Location: Cleveland OH
Sponsor: Jay Alberts

Sex: All

Age: 18+

Code: NCT06442033

Recruiting
Active & Responsive

Neuroimaging of Parkinson's

for
Parkinsons Disease (PD)
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 40+

Code: NCT07024875

Recruiting
Active & Responsive

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for
Multiple System Atrophy, Parkinsons Disease
Location: Lexington KY
Sponsor: Craig van Horne, MD, PhD

Sex: All

Age: 40 - 70+

Code: NCT06683365

Phase1, Recruiting
Active & Responsive

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

for
Essential Tremor, Movement Disorders, Essential Tremor,
Location: Orlando FL, Louisville KY, Memphis TN, Scottsdale AZ
Sponsor: CND Life Sciences

Sex: All

Age: 50 - 70+

Code: NCT07428447

Recruiting
New

A Trial Investigating Lu AF28996 in Adults With Parkinson's Disease Who Have Motor Fluctuations

for
Parkinson's Disease
Location: Farmington Hills MI, Round Rock TX
Sponsor: H. Lundbeck A/S

Sex: All

Age: 40 - 70+

Code: NCT07514858

Phase2, Recruiting
New

A Comparative Performance Study Between High and Standard Resolution Positron Emission Tomography Camera Using [18F] AV-133 in Prodromal Parkinson's Disease

for
Prodromal Parkinson's Disease
Location: New Haven CT
Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All

Age: 18+

Code: NCT07809438

Phase2, Recruiting
New

Optimizing Adaptive DBS for Parkinson's Disease

for
PARKINSON DISEASE (Disorder)
Location: Davis CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT07798271

Recruiting
New

Biofluid Research on Age-Related or Inherited Neurodegeneration

for
Frontotemporal Degeneration (FTD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07798700

Recruiting
New

Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation

for
PARKINSON DISEASE (Disorder)
Location: Richardson TX
Sponsor: The University of Texas at Dallas

Sex: All

Age: 50 - 70+

Code: NCT07534397

Recruiting