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Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

for
Sarcoma, Endocrine Tumors, Neuroblastoma, Retinoblastoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT01109394

Recruiting

Investigation of Impact of AI on Prostate Cancer Workflow

for
Prostate Cancer, Prostatic Neoplasm, Cancer of the Prostate,
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 55 - 70+

Code: NCT07084779

Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

for
Metastatic Oral Cavity Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06997068

Phase2, Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

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Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06910761

Phase2, Recruiting

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

for
Clinical Stage III Gastric Cancer AJCC v8,
Location: Houston TX
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06364410

Phase1, Recruiting

Prospective Registry of Histotripsy for Soft Tissue Tumors

for
Soft Tissue Neoplasm, Soft Tissue Cancer, Soft Tissue Lesion
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT07470008

Recruiting

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

for
Relapsed Pediatric ALL, Hematopoietic Cell Transplantation,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT07257419

Phase1, Recruiting

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for
Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma,
Location: Boston MA, Newton MA, Commack NY, Uniondale NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227415

Phase1, Phase2, Recruiting

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for
Bladder Cancer, Muscle-Invasive Bladder Carcinoma,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18 - 70+

Code: NCT07234968

Recruiting

UCSF PANC Cyst Registry

for
Pancreatic Cyst, Pancreatic Neoplasms, Pancreatic Cancer,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT04291651

Recruiting

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693377

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for
Advanced Malignant Solid Neoplasm,
Location: Brewer ME, Augusta ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT05564377

Phase2, Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

for
Malignant Glioma of Brain, Astrocytoma, Malignant Astrocytoma,
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT05686798

Phase1, Recruiting

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

for
Hepatocellular Carcinoma, Liver Cancer, Adult, Liver Neoplasm,
Location: The Bronx NY, Dallas TX, Seattle WA, Portland OR,
Sponsor: Eureka Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04864054

Phase1, Phase2, Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

for
Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer,
Location: Toronto, Pittsburgh PA, Milwaukee WI, Houston TX
Sponsor: UMC Utrecht

Sex: All

Age: 18+

Code: NCT04075305

Recruiting

Mayo Clinic Upper Digestive Disease Survey

for
Esophageal Neoplasms, Cancer of Esophagus,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT02530983

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for
Cancer, Advanced Cancer, Locally Advanced Carcinoma,
Location: Fairfax VA, Sarasota FL, Nashville TN, St Louis MO,
Sponsor: Angiex, Inc.

Sex: All

Age: 18+

Code: NCT06440005

Phase1, Recruiting

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05376878

Recruiting