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Active & Responsive

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07361562

Phase 1, Recruiting
Active & Responsive

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

for
Glioblastoma Multiforme (GBM), Glioblastoma, Glioma of Brain,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18 - 70+

Code: NCT03213002

Phase 1, Phase 2, Recruiting
Active & Responsive

Biennial CEM in Women With a Personal History of Breast Cancer

for
Breast Cancer, Breast Neoplasms, Breast Cancer Female,
Location: Monroeville PA, West Mifflin PA, Pittsburgh PA,
Sponsor: Wendie Berg

Sex: Female

Age: 30 - 70+

Code: NCT06105749

Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

for
Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms,
Location: Boston MA, Norfolk VA, Detroit MI, Centerville OH,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05386108

Phase 1, Phase 2, Recruiting

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Active & Responsive

PAS-004 in Patients With Advanced Solid Tumors

for
RAS Mutation, NF1 Mutation, RAF Mutation, Advanced Solid Tumors
Location: Fairfax VA, Irving TX, San Antonio TX
Sponsor: Pasithea Therapeutics Corp.

Sex: All

Age: 18+

Code: NCT06299839

Phase 1, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase 1, Phase 2, Recruiting
Active & Responsive

Biomarkers to Detect Endocrine Therapy Resistance

for
Metastatic Cancer, Breast Cancer, Lobular Breast Carcinoma
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT06067503

Phase 2, Recruiting
Active & Responsive

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

for
Localized Renal Pelvis and Ureter Urothelial Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT01050504

Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase 1, Recruiting
Active & Responsive

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

for
Pheochromocytoma, Paraganglioma, Inherited Cancer Syndrome,
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 0+

Code: NCT03160274

Recruiting
Active & Responsive

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

for
Clear Cell Renal Cell Cancer (ccRCC),
Location: San Francisco CA
Sponsor: Kelly Fitzgerald, MD

Sex: All

Age: 18+

Code: NCT07043608

Phase 2, Recruiting
Active & Responsive

Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.

for
Reccurent/Metastatic Solid Tumor Disease,
Location: Quebec
Sponsor: CHU de Quebec-Universite Laval

Sex: Male

Age: 18+

Code: NCT07483658

Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting
Active & Responsive

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma in Relapse, Myeloma Multiple,
Location: Boston MA, Hackensack NJ, Tampa FL, Atlanta GA,
Sponsor: Kelonia Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07075185

Phase 1, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07477886

Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, Fairfax VA, Nashville TN, Saint Paul MN,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase 1, Phase 2, Recruiting
Active & Responsive

Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06414278

Recruiting