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A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

for
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia,
Location: Miami FL, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06566742

Phase 2, Recruiting

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

for
Non Small Cell Lung Cancer, NSCLC, KRAS G12C
Location: Richmond VA, Charlottesville VA, Columbus OH
Sponsor: Ryan Gentzler, MD

Sex: All

Age: 18+

Code: NCT06248606

Phase 2, Recruiting

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

for
Breast Cancer, Breast Cancer Female, Muscle Weakness
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston

Sex: Female

Age: 18 - 70+

Code: NCT06395506

Recruiting

A Study to Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients

for
Solid Tumor
Location: Houston TX, Dallas TX, Glendale CA
Sponsor: Teligene US

Sex: All

Age: 18+

Code: NCT06010342

Phase 2, Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: New York NY, Philadelphia PA, Durham NC, Toronto,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04065399

Phase 1, Phase 2, Recruiting

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Study of the Farnesyl Transferase Inhibitor, R115777, in Combination With Topotecan (NYU 99-32)

for
Cancer
Location: New York NY
Sponsor: National Center for Research Resources (NCRR)

Sex: All

Age: 18+

Code: NCT00006199

Phase 1, Recruiting

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for
Endometrial Cancer
Location: Boston MA, Providence RI, Worcester MA, Springfield MA,
Sponsor: Canadian Cancer Trials Group

Sex: Female

Age: 18+

Code: NCT05640999

Phase 2, Recruiting

SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

for
Brain Metastases, HR+ Metastatic Breast Cancer
Location: Columbus OH
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT04923542

Phase 1, Phase 2, Recruiting

Exercise Post Bone Marrow Transplant

for
Leukemia
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 18+

Code: NCT02320942

Recruiting

Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)

for
Breast Cancer, Breast Cancer Female
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05561842

Recruiting

Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, Hepatotoxicity
Location: Orange CA
Sponsor: Children's Hospital of Orange County

Sex: All

Age: 5 - 29

Code: NCT05501899

Early Phase 1, Recruiting

HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

for
Prostatic Neoplasms
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: Male

Age: 0+

Code: NCT01913106

Phase 1, Phase 2, Recruiting

ExoDx Prostate Evaluation in Active Surveillance Patient Population

for
Prostate Cancer
Location: Towson MD
Sponsor: Exosome Diagnostics, Inc.

Sex: Male

Age: 45+

Code: NCT05572099

Recruiting

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT04762199

Phase 1, Recruiting

Stereotactic Ablative Radiation Therapy for Abiraterone-Resistant, Oligoprogressive Metastatic Prostate Cancer

for
Oligoprogressive, Castration-Resistant Prostate Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: Male

Age: 18+

Code: NCT04838899

Recruiting

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

for
Lung Neoplasms, Lung Cancer
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 40 - 54

Code: NCT04577599

Recruiting

Prostate Boost Irradiation With Stereotactic Body RT (SBRT)

for
Prostate Cancer
Location: St. Catharines, Hamilton
Sponsor: Juravinski Cancer Center

Sex: Male

Age: 18 - 70+

Code: NCT03380806

Phase 2, Recruiting

Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma

for
Non-hodgkin Lymphoma
Location: Quebec, Montreal, Ottawa, Toronto, Hamilton, Regina,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT05998642

Phase 2, Recruiting

(3D) Ultrasound Imaging Liver and Kidney

for
Liver Cancer, Kidney Cancer
Location: London
Sponsor: Western University, Canada

Sex: All

Age: 18+

Code: NCT03844399

Recruiting

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

for
Breast Cancer, Hereditary Breast and Ovarian Cancer
Location: Lee's Summit MO, Kansas City MO, Kansas City KS,
Sponsor: University of Kansas Medical Center

Sex: All

Age: 0+

Code: NCT02302742

Recruiting