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Active & Responsive

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for
Solid Tumor
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06384807

Phase 1, Phase 2, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Westerly RI, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase 2, Phase 3, Recruiting
Active & Responsive

Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)

for
Autism Spectrum Disorder (ASD)
Location: Baltimore MD, Orange CA
Sponsor: Children's Hospital of Orange County

Sex: Male

Age: 5 - 14

Code: NCT06866275

Phase 2, Recruiting
Active & Responsive

Biofeedback Training for Hemianopia

for
Hemianopia, Brain Injuries
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 70+

Code: NCT06995313

Recruiting
Active & Responsive

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for
Castration Levels of Testosterone,
Location: Brewer ME, Bath ME, Portland ME, Scarborough ME,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT03678025

Phase 3, Recruiting

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Active & Responsive

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

for
Muscle Weakness, Problems Moving Their Arms and Legs
Location: Bethesda MD
Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All

Age: 5 - 25

Code: NCT06998134

Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield MA, Saint Johnsbury VT, Lebanon NH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase 2, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Waterford CT, New Haven CT, Stony Brook NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: Kentville, Boston MA, Providence RI, Levis,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase 3, Recruiting
Active & Responsive

Restoration of Hand Function in Cervical SCI

for
Spinal Cord Injury Cervical
Location: Cleveland OH
Sponsor: MetroHealth Medical Center

Sex: All

Age: 18+

Code: NCT06611748

Recruiting
Active & Responsive

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

for
Myasthenia Gravis, Generalized Myasthenia Gravis
Location: Philadelphia PA, Miami FL, Indianapolis IN, Columbia MO,
Sponsor: Kyverna Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06193889

Phase 2, Phase 3, Recruiting
Active & Responsive

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Saint Johnsbury VT, Lebanon NH, Commack NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase 3, Recruiting
Active & Responsive

Pain Outcomes Associated With Exogenous Hormone Therapy in Adults

for
Pain, Gender Minority Individuals
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18 - 50

Code: NCT06939257

Recruiting
Active & Responsive

PCS in Severe Treatment Resistant Depression

for
Treatment Resistant Depression
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 22 - 70

Code: NCT04124341

Recruiting
Active & Responsive

Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)

for
Borderline Personality Disorder (BPD),
Location: Toronto
Sponsor: Joshua Rosenblat

Sex: All

Age: 18 - 70

Code: NCT07569198

Phase 2, Recruiting
Active & Responsive

Cardiometabolic Risk Effects of Short-term Cessation of Neurostimulation Therapy

for
Obstructive Sleep Apnea, Obstructive Sleep Apnea of Adult
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT06720545

Recruiting
Active & Responsive

Positive Processes and Transition to Health - Single-Session (PATH-SS)

for
PTSD, Depression
Location: Cleveland OH
Sponsor: Case Western Reserve University

Sex: All

Age: 18 - 65

Code: NCT06900712

Recruiting
Active & Responsive

Characterizing Synaptic Density in Treatment Resistant Depression

for
Treatment Resistant Depression,
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 25 - 65

Code: NCT03537794

Recruiting
Active & Responsive

Identification and Validation of Epigenetic Biomarkers of PMDD

for
PMDD, Premenstrual Dysphoric Disorder (PMDD),
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: Female

Age: 18 - 50

Code: NCT06771583

Recruiting
Active & Responsive

Listening Effort in Cochlear Implant Users

for
Auditory Perception; Abnormal, Hearing Loss, Sensorineural,
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18 - 70+

Code: NCT06516575

Recruiting