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Active & Responsive

Biobank for Cholestatic Liver Diseases.

for
Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT03445585

Recruiting
Active & Responsive

taVNS for Persistent Symptoms From Lyme Disease

for
Post-Treatment Lyme Disease
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18 - 65

Code: NCT05776251

Recruiting
Active & Responsive

Psilocybin Therapy for Depression in Parkinson's Disease

for
Parkinson Disease, Depression
Location: San Francisco CA
Sponsor: Joshua Woolley, MD, PhD

Sex: All

Age: 40 - 70+

Code: NCT06455293

Phase2, Recruiting
Active & Responsive

HER-2 B Cell Peptide Vaccine

for
Metastatic Breast Cancer, HER2-positive Breast Cancer,
Location: Indianpolis IN
Sponsor: Pravin T.P Kaumaya

Sex: All

Age: 18+

Code: NCT06414733

Phase1, Recruiting
Active & Responsive

Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform

for
Shwachman-Diamond Syndrome, SDS, IBMF, Congenital Neutropenia,
Location: Woburn MA
Sponsor: Shwachman-Diamond Syndrome Alliance Inc

Sex: All

Age: 0+

Code: NCT06999954

Recruiting

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Active & Responsive

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

for
Ovarian Cancer, Fallopian Tube Cancer
Location: Boston MA, New York NY, Philadelphia PA, St Louis MO,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05287451

Recruiting
Active & Responsive

WBSI Guided Personalized Delivery of TTFields

for
GBM, Glioma Glioblastoma Multiforme, Tumor, Brain
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 22+

Code: NCT05086497

Recruiting
Active & Responsive

Mediterranean Diet Versus Western Diet on Fatigue in Autoimmune Hepatitis Patients

for
Autoimmune Hepatitis
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT06250309

Recruiting
Active & Responsive

Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia

for
Friedreich Ataxia, Cardiomyopathies, Cardiac Hypertrophy,
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 12 - 50

Code: NCT05302271

Phase1, Recruiting
Active & Responsive

OUD (Opioid Use Disorder) Target Trial

for
Opioid Use Disorder
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06585709

Recruiting
Active & Responsive

Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes

for
Diabetes Mellitus, Type 1
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 65

Code: NCT06503809

Recruiting
Active & Responsive

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

for
Breast Cancer
Location: Columbus OH, Chicago IL, Iowa City IA
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06169371

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Boston MA, Waterford CT, Guilford CT, New Haven CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & Responsive

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

for
Drug Resistant Epilepsy, Epilepsy, Seizures, Focal, Seizure,
Location: Boston MA, Charlottesville VA, Palo Alto CA
Sponsor: NaviFUS Corporation

Sex: All

Age: 18+

Code: NCT06388707

Phase1, Phase2, Recruiting
Active & Responsive

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for
Solid Tumor
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06384807

Phase1, Phase2, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Westerly RI, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting
Active & Responsive

Biofeedback Training for Hemianopia

for
Hemianopia, Brain Injuries
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 70+

Code: NCT06995313

Recruiting
Active & Responsive

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

for
Muscle Weakness, Problems Moving Their Arms and Legs
Location: Bethesda MD
Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All

Age: 5 - 25

Code: NCT06998134

Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield MA, Saint Johnsbury VT, Lebanon NH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase2, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Waterford CT, New Haven CT, Stony Brook NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase2, Recruiting