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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: New Haven CT, Washington D.C. DC, Winston-Salem NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase3, Recruiting
Featured

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for
Diabetic Retinopathy
Location: Portland ME, Bloomfield NJ, Hagerstown MD,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07592273

Phase2, Phase3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for
Hemophilia A
Location: Miami FL, Tampa FL, London, Ann Arbor MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 12+

Code: NCT07416604

Phase3, Recruiting
Featured

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

for
Hemophilia A
Location: Orange CA, Vallejo CA, San Francisco CA
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07226206

Phase1, Phase2, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for
Obesity or Overweight
Location: Boston MA, Needham MA, New Haven CT, Quebec,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351045

Phase3, Recruiting

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Featured

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Tampa FL, Newnan GA, Grand Rapids MI, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07409246

Phase1, Recruiting
Featured

A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies

for
Gynecologic Cancers, Platinum-Sensitive Ovarian Cancer,
Location: Providence RI, Teaneck NJ, Syracuse NY, Fairfax VA,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT07024784

Phase2, Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for
Diabetic Macular Edema
Location: Philadelphia PA, Baltimore MD, Lynchburg VA, Erie PA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07425522

Phase1, Recruiting
Featured

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non-Small Cell Lung Cancer
Location: Winter Haven FL, Athens GA, Cincinnati OH, Lexington KY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06236438

Phase2, Phase3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for
Obesity or Overweight, Type 2 Diabetes Mellitus
Location: Quebec, Sherbrooke, Montreal, Morehead City NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351058

Phase3, Recruiting
Featured

A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

for
Moderately to Severely Active Ulcerative Colitis
Location: Hartford CT, Lake Success NY, New York NY, Toronto,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 2 - 17

Code: NCT07158242

Phase3, Recruiting
Featured

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

for
Idiopathic Pulmonary Fibrosis
Location: Trois-Rivieres, Philadelphia PA, Richmond VA,
Sponsor: AbbVie

Sex: All

Age: 40+

Code: NCT07230288

Phase2, Recruiting
Featured

To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

for
Breast Cancer
Location: East Brunswick NJ, Jacksonville FL, Kansas City MO,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07368998

Phase2, Recruiting
Featured

Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks

for
Migraine
Location: Naperville IL, Grand Island NE, Aliso Viejo CA
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07310290

Recruiting
Featured

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Cancer
Location: Providence RI, The Bronx NY, Montreal, Myrtle Beach SC,
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07287150

Phase2, Recruiting
Featured

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, New Haven CT, Fairfax VA, Ocala FL, Tampa FL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07155174

Phase2, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Montreal, Toronto, Huntersville NC, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase1, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Boston MA, New Haven CT, New York NY, Commack NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for
Neovascular Age-related Macular Degeneration
Location: Portland ME, Little Silver NJ, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07007065

Phase3, Recruiting
Featured

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: Morehead City NC, Newport News VA, New Bern NC,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting