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A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)

for
Ovarian Cancer, Ovarian Neoplasms, Peritoneal Cancer,
Location: Washington D.C. DC, Fort Worth TX
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07776691

Phase3, Recruiting
Active & ResponsiveNew

Postural Motor Activation Deficits After mTBI; Translating Laboratory Findings to Clinical Care

for
Mild Traumatic Brain Injury (mTBI),
Location: Salt Lake City UT, Portland OR
Sponsor: Oregon Health and Science University

Sex: All

Age: 18 - 60

Code: NCT07549529

Recruiting
Active & ResponsiveNew

Lower Body Negative Pressure to Validate Physiological Monitors

for
Physiological Stress
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 55

Code: NCT07840144

Recruiting
Active & ResponsiveNew

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

for
Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18 - 70+

Code: NCT07840183

Recruiting
New

Anchoring and Postural Stability

for
Healthy Adult Participants
Location: Orlando FL
Sponsor: University of Central Florida

Sex: All

Age: 18 - 50

Code: NCT07837778

Recruiting

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Post-op Prednisone and Glucose Monitoring in TKA

for
Osteoarthritis, Unicompartmental Knee Arthroplasty,
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT07630896

Recruiting
Active & ResponsiveNew

Teen and Adult Tic TMS Study

for
Tic Disorder
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 15 - 35

Code: NCT07839377

Recruiting
New

Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD

for
NMOSD
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07010302

Recruiting
New

A Pilot Investigation of Pain Reprocessing Therapy for Functional Dyspepsia

for
Functional Dyspepsia
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07838324

Recruiting
Active & ResponsiveNew

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

for
Overweight , Obesity, Adults
Location: New York NY, Wilmington NC, Orlando FL, Nashville TN,
Sponsor: Alveus Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07837973

Phase2, Recruiting
New

A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)

for
Healthy
Location: Marlton NJ, Hollywood FL, Cleveland OH
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 64

Code: NCT07743151

Phase1, Recruiting
New

Bright Light Therapy in Patients With Melanoma or Non-small Cell Lung Cancer (NSCLC) Who Are Receiving First-Line Immune Checkpoint Blockade

for
Melanoma (Skin Cancer), NSCLC (Non-small Cell Lung Cancer)
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT07661966

Recruiting
New

Mobile Sun Health Intervention EnabLing Daily Protection

for
Skin Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18 - 29

Code: NCT07830394

Recruiting
New

A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

for
Nasal Polyps
Location: Plano TX
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07782957

Phase3, Recruiting
New

This Protocol is a Sub-study Under the PPMI Program. It is a Longitudinal, Single-center Study to Assess the Performance of [18F]AV-133 Imaging Using High and Standard Resolution PET in Individuals Enrolled With Parkinson's Disease (PD) for up to 12 Months.

for
Parkinson's Disease (PD), Healthy Control Subjects
Location: New Haven CT
Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All

Age: 18+

Code: NCT07830654

Phase2, Recruiting
Active & ResponsiveNew

Remote Monitoring Using a Digital Platform

for
Chronic Pain
Location: Hackensack NJ, Paramus NJ
Sponsor: Hackensack Meridian Health

Sex: All

Age: 18+

Code: NCT07837102

Recruiting
Active & ResponsiveNew

Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPH

for
Nocturia
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: Female

Age: 60+

Code: NCT07829029

Recruiting
New

A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer

for
Colorectal Cancer (Locally Advanced or Metastatic)
Location: Faifax VA, Houston TX
Sponsor: SOTIO Biotech a.s.

Sex: All

Age: 18+

Code: NCT07693751

Phase1, Phase2, Recruiting
New

Protoacoustic Imaging For 3D Mapping

for
Proton Therapy, Radiation Therapy, Secondary Skin Reactions,
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 18+

Code: NCT07832617

Recruiting
New

Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment

for
Refractory Migraine, Headache
Location: Camden NJ
Sponsor: Daniel A Tonetti, MD

Sex: All

Age: 18+

Code: NCT07361549

Phase2, Recruiting