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A remote clinical trial is a research study where some or all of your participation happens away from a study site. Researchers call this a decentralized clinical trial. In practice it can mean video visits with the study doctor, questionnaires completed on your phone, a study medicine delivered by courier, blood draws at a local lab or by a visiting nurse, and a wearable device that sends data automatically. Fully online studies exist, especially surveys, digital therapy programs, and studies of conditions like depression, insomnia, or migraine where symptoms are tracked by diary. Most drug trials are hybrid: a first visit in person for consent and baseline tests, then follow up largely from home.
The model grew fast during the pandemic and stayed. In September 2024 the FDA issued final guidance on how sponsors may run trials with remote elements, covering telehealth visits, home nursing, local labs, and digital data collection, which gave researchers a clear framework and made remote designs standard rather than experimental. The practical result for participants is a wider door: studies that once required living near an academic center can now enroll people hundreds of miles away. Our guides explain how decentralized trials work, what a fully virtual study involves, and how remote monitoring keeps participants safe.
Fully online studies. Surveys, registries, and app based programs where you never visit a site. Common for mental health, sleep, chronic pain, and long term follow up of people with a diagnosis. Consent is signed electronically and study contact happens by video, phone, or app.
Hybrid drug trials. One or two in person visits for screening and baseline tests, then medicine shipped to you and follow up by telehealth. Blood work is done at a local lab or by a nurse who comes to your home. This is now the most common remote design in medicine trials.
Home visit studies. A research nurse brings the study to you: vital signs, blood draws, injections, and device checks at your kitchen table. Used for conditions that make travel hard and for older participants.
Digital health and wearable studies. A watch, patch, or sensor collects data continuously, for example heart rhythm, sleep, blood sugar, or activity, and researchers compare it against symptoms or treatment. You may never speak to a study team member unless something needs follow up.
Digital therapeutics. Trials of app delivered therapy, such as cognitive behavioral programs for insomnia or anxiety, where the app itself is the treatment being tested.
Remote studies have the same medical eligibility rules as any other study: a diagnosis, an age range, sometimes a lab value or treatment history. What they add is practical requirements. Most need a smartphone or computer with internet, an address where a courier can deliver, and, for hybrid studies, willingness to attend a small number of in person visits or let a nurse visit at home. Some studies enroll only within certain states because of medical licensing rules for telehealth. Fully online surveys and registries usually have the widest eligibility of any research and often enroll healthy volunteers too. Eligibility always varies by study.
Real remote studies are registered on ClinicalTrials.gov, run by a named sponsor and study doctor, and reviewed by an ethics board. They will never ask you to pay to join, and consent is always documented. Every study on this platform is a registered clinical trial with a listed sponsor.
Usually a smartphone or computer with internet. When a study requires a specific device, such as a wearable sensor or a tablet, it is normally provided by the study team and returned at the end.
Identify your study. Use the filters to combine a condition with the remote or online option, and read the study description for how much of it happens at home. Titles often say "remote," "virtual," "decentralized," or "telehealth."
Check the practical requirements. Click "Learn More" to see whether a device is provided or you use your own, how medicines are delivered, whether any in person visits are needed, and which states the study can enroll from.
Complete the health profile. Click "Get started" to begin the 5-step application. Have three things ready: your diagnosis and current medicines, your state of residence, and whether you can attend occasional in person or home visits if the study is hybrid.
Submit the application. A study coordinator reviews it and contacts you, usually by phone or video. Nothing is decided until you have gone through informed consent, which in remote studies is typically done over video and signed electronically, and participation is voluntary at every step.