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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

for
Breast Cancer, HER2-negative Breast Cancer,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT04573231

Phase2, Recruiting

A Study of the Preliminary Efficacy of DARE-HPV to Treat High-risk Persistent Human Papillomavirus (hrHPV)

for
Human Papilloma Virus (HPV),
Location: Little Rock AR, Layton UT, Phoenix AZ, Seattle WA
Sponsor: Daré Bioscience, Inc.

Sex: Female

Age: 22 - 50

Code: NCT07601074

Phase2, Recruiting

To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

for
Locally Advanced or Metastatic HER2-Expressing Cancers
Location: Duarte CA
Sponsor: Vir Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT05356741

Phase1, Phase2, Recruiting

Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer

for
HER2-negative Breast Cancer, HER2 Negative Breast Carcinoma,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06774027

Recruiting

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for
Melanoma (Skin Cancer),
Location: Lake Success NY, Fairfax VA, Detroit MI, Cincinnati OH,
Sponsor: Aminex Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07287917

Phase1, Phase2, Recruiting

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Rapid HIV, Hep C, and Syphilis Screening in a Rural Street Medicine Clinic

for
HIV Testing, HEPATITIS C (HCV), Syphilis,
Location: Harpers Ferry WV
Sponsor: West Virginia University

Sex: All

Age: 18+

Code: NCT07317687

Recruiting

Rash & Diarrhea Prophylaxis With Capivasertib

for
Metastatic HR+/HER2- Breast Cancer
Location: New Haven CT
Sponsor: Maryam Lustberg

Sex: All

Age: 18+

Code: NCT07426822

Phase2, Recruiting

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

for
Influenza, Community-acquired Pneumonia, Cardiovascular Events
Location: Oakland CA
Sponsor: Kaiser Permanente

Sex: All

Age: 65+

Code: NCT06029933

Recruiting

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

for
ER-Positive HER2-Negative Breast Cancer
Location: Marietta GA, Kingwood TX
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07647328

Phase3, Recruiting

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

for
HER2-negative, Gastroesophageal Junction,
Location: Boston MA, New York NY, Albany NY
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07546812

Phase2, Recruiting

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

for
Head and Neck Carcinoma of Unknown Primary,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04754321

Phase1, Recruiting

Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07407920

Phase2, Recruiting

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

for
Brain Cancer, Brain Metastases, Melanoma, Lung Cancer,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT04899908

Phase2, Recruiting

A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults

for
Influenza, Human+COVID-19
Location: Newport News VA, Charlottesville VA, West Palm Beach FL,
Sponsor: GlaxoSmithKline

Sex: All

Age: 65 - 70+

Code: NCT07464314

Phase1, Recruiting

ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

for
HER2 Low Breast Carcinoma, Triple Negative Breast Cancer,
Location: San Francisco CA
Sponsor: Laura Huppert, MD, BA

Sex: All

Age: 18+

Code: NCT06224673

Phase2, Recruiting

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, EGFR Mutation,
Location: Nashville TN
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT05099172

Phase1, Phase2, Recruiting

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Chicago IL, Warrenville IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT07178301

Phase2, Recruiting

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

for
HR+/HER2- Breast Cancer
Location: Shirley NY, Mineola NY, New York NY, Brooklyn NY,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07492641

Phase3, Recruiting

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

for
Squamous Cell Carcinoma, Human Papilloma Virus (HPV),
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT07513389

Phase2, Recruiting

Capecitabine in ER+/HER2-negative Breast Cancer

for
ER-positive, HER2-negative Breast Cancer, Breast Cancer Stage I,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07631052

Phase2, Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial