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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05541016

Phase2, Recruiting

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

for
HPV-Negative Squamous Cell Carcinoma
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06005324

Phase1, Recruiting

Alpelisib, Fulvestrant and Dapagliflozin for the Treatment of HR+, HER2 -, PIK3CA Mutant Metastatic Breast Cancer

for
Metastatic Breast Cancer, HER2-negative Breast Cancer
Location: Kansas City MO
Sponsor: Saint Luke's Health System

Sex: All

Age: 18 - 65

Code: NCT05025735

Phase2, Recruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06662058

Recruiting

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

for
HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer,
Location: New York NY
Sponsor: Stephen E. Goldstone

Sex: All

Age: 18 - 70+

Code: NCT03302858

Phase2, Recruiting

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Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca

for
HPV-Related Squamous Cell Carcinoma
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT04988074

Phase2, Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for
High Grade Epithelial Ovarian Cancer,
Location: Boston MA, Providence RI, Camden NJ, Doylestown PA,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT05579366

Phase1, Phase2, Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

for
Cervical Cancer, Throat Cancer, Oropharynx Cancer, Anal Cancer,
Location: New Brunswick NJ, Bethesda MD
Sponsor: Christian Hinrichs

Sex: All

Age: 18+

Code: NCT05686226

Phase2, Recruiting

PRE-ISPY Phase I/II Oncology Platform Program

for
HER2-positive Breast Cancer, Metastatic Cancer,
Location: Birmingham AL, Chicago IL, Orland Park IL, New Lenox IL,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: All

Age: 18+

Code: NCT05868226

Phase1, Phase2, Recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

for
HPV-Related Cervical Carcinoma,
Location: Orlando FL, Tampa FL, Tulsa OK
Sponsor: Theravectys S.A.

Sex: All

Age: 18+

Code: NCT06319963

Phase1, Phase2, Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

for
Sarcoma, HER-2 Protein Overexpression, Osteosarcoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 1 - 25

Code: NCT04995003

Phase1, Recruiting

Oropharynx (OPX) Biomarker Trial

for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06356272

Recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

for
HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma,
Location: New Brunswick NJ
Sponsor: Christian Hinrichs

Sex: All

Age: 18+

Code: NCT05639972

Phase1, Phase2, Recruiting

Alcohol and Sexual Communication Among Couples in the Laboratory

for
Alcohol Intoxication, Intimate Partner Violence (IPV),
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 21 - 65

Code: NCT06865872

Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors

for
Locally Advanced or Metastatic ER+ HER2- Breast Cancer,
Location: New Haven CT, Edgewood KY, Louisville KY, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT04606446

Phase2, Recruiting

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

for
Cancer of the Head and Neck, Oropharynx Cancer,
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT04444869

Phase2, Recruiting

Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Boston MA, Rochester NY, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 65+

Code: NCT06042569

Phase2, Recruiting

Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

for
HPV-unrelated Head and Neck Squamous Cell Carcinoma
Location: St Louis MO, Fargo ND, Sioux Falls SD
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04966481

Phase3, Recruiting

TRUDI: TDXD+Durva in HER2+/Low IBC

for
Invasive Breast Cancer, Inflammatory Breast Cancer Stage III,
Location: Boston MA, Houston TX
Sponsor: Filipa Lynce, MD

Sex: Female

Age: 18+

Code: NCT05795101

Phase2, Recruiting

The Role of Dentists in Human Papillomavirus Vaccination

for
HPV
Location: Winterville NC
Sponsor: East Carolina University

Sex: All

Age: 18 - 70+

Code: NCT04757701

Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial