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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06088381

Phase2, Recruiting

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05098210

Phase1, Recruiting

Role of the Immune Environment in Response to Therapy in Breast Cancer

for
Breast Cancer, ER Positive Breast Cancer,
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 18+

Code: NCT05396612

Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT05464810

Early_phase1, Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

for
HPV, Throat Cancer, Oropharyngeal Carcinoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05491512

Phase2, Recruiting

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Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

for
Hpv
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 9 - 17

Code: NCT06380114

Recruiting

Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy

for
Oropharyngeal Cancers, HPV, Tonsil Cancer,
Location: Clinton MD, Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT06902623

Recruiting

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

for
Metastatic Breast Cancer, Stage IV Breast Cancer, Breast Cancer,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06678269

Phase1, Recruiting

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

for
HPV, Oropharynx Cancer, HPV-Related Carcinoma,
Location: Commack NY, Rockville Centre NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05307939

Phase2, Recruiting

Respiratory Virus Sampling and Repository

for
Influenza, COVID-19
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 3+

Code: NCT05266222

Recruiting

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

for
Breast Cancer, HER2-low Breast Cancer, Metastatic Breast Cancer,
Location: Boston MA, New Haven CT, The Bronx NY,
Sponsor: Ana C Garrido-Castro, MD

Sex: All

Age: 18+

Code: NCT06533826

Phase2, Recruiting

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Columbus OH
Sponsor: Margaret Gatti-Mays

Sex: All

Age: 18+

Code: NCT06026657

Phase1, Phase2, Recruiting

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

for
Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B,
Location: Memphis TN, Fridley MN, Minneapolis MN, Coon Rapids MN,
Sponsor: Helio Genomics

Sex: All

Age: 18+

Code: NCT05181826

Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC),
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT06052839

Phase2, Recruiting

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

for
Advanced HR+/HER2- Breast Cancer,
Location: Atlanta GA, Nashville TN, San Antonio TX
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07288359

Phase1, Phase2, Recruiting

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

for
Breast Cancer, TNBC - Triple-Negative Breast Cancer,
Location: Westbury NY, New Brunswick NJ, Baltimore MD, Miami FL,
Sponsor: Processa Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06568692

Phase2, Recruiting

Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers

for
Metastatic Breast Cancer, Triple Negative Breast Cancer,
Location: Durham NC, Buffalo NY, Atlanta GA, Lexington KY,
Sponsor: Kathy Miller

Sex: All

Age: 18+

Code: NCT05846789

Phase2, Recruiting

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Location: New York NY, Paramus NJ
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT05419089

Phase2, Recruiting

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for
Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG,
Location: Halifax, Montreal, Syracuse NY, Myrtle Beach SC,
Sponsor: Theralase® Technologies Inc.

Sex: All

Age: 18+

Code: NCT03945162

Phase2, Recruiting

Dime La VerDAD: Verify, Debunk, and Disseminate

for
Influenza, COVID-19, Communication Research, Health Behavior,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18 - 70+

Code: NCT06417762

Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial