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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Vaccine Immunity and Inflammation in the Aging Person Living With HIV

for
HIV Infections, Age
Location: Minneapolis MN
Sponsor: Hennepin Healthcare Research Institute

Sex: All

Age: 18+

Code: NCT06514547

Recruiting

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

for
Low Grade Glioma of Brain
Location: Durham NC
Sponsor: Katy Peters, MD, PhD

Sex: All

Age: 18+

Code: NCT05609994

Phase1, Recruiting

Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection

for
EBV, Epstein-Barr Virus Infection, Infectious Mononucleosis,
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 29

Code: NCT06908096

Phase1, Recruiting

Safety, and Efficacy Study of ShigETEC, a Live, Attenuated, Oral Combination Vaccine to Prevent Shigella and ETEC Disease Delivered to Healthy Adults Ages 18 to 50 Years Old

for
Shigella
Location: Baltimore MD
Sponsor: Eveliqure Biotechnologies GmbH

Sex: All

Age: 18 - 50

Code: NCT07049159

Phase2, Recruiting

A Safety and Immunogenicity Study of CHIKV VLP Vaccine in Children.

for
Chikungunya Virus
Location: Washington D.C. DC, Miami FL, Cincinnati OH,
Sponsor: Bavarian Nordic

Sex: All

Age: 1 - 11

Code: NCT07003984

Phase3, Recruiting

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Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy

for
Breast Cancer, Triple Negative Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06435351

Early_phase1, Recruiting

Safety of the Herpes Zoster Subunit Vaccine in Lupus

for
Systemic Lupus Erythematosus
Location: New York NY, Oklahoma City OK
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05559671

Recruiting

Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm

for
Myelofibrosis, Essential Thrombocythemia, MPN
Location: New York NY
Sponsor: Marina Kremyanskaya

Sex: All

Age: 18+

Code: NCT05025488

Phase1, Recruiting

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

for
Pediatric Recurrent Central Nervous System Tumors
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 0 - 25

Code: NCT03988283

Phase1, Recruiting

Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

for
Cytomegaloviral Infection,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 1 - 21

Code: NCT03354728

Phase1, Phase2, Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

for
Stage III Hepatocellular Carcinoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03942328

Phase1, Phase2, Recruiting

Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

for
Warts
Location: Salt Lake City UT
Sponsor: Western Institute for Veterans Research

Sex: All

Age: 18+

Code: NCT05625633

Phase2, Phase3, Recruiting

Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05183854

Phase2, Recruiting

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Charlottesville VA, Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: Female

Age: 18+

Code: NCT04348747

Phase2, Recruiting

TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery

for
Breast Adenocarcinoma, Stage II Breast Cancer AJCC v6 and v7,
Location: Lebanon NH, Pinehurst NC, Jacksonville FL,
Sponsor: Academic and Community Cancer Research United

Sex: Female

Age: 18+

Code: NCT04197687

Phase2, Recruiting

Immunogenicity of COVID-19 Vaccination in PLWH

for
HIV Infections
Location: Montreal, Toronto
Sponsor: CIHR Canadian HIV Trials Network

Sex: All

Age: 16+

Code: NCT04894448

Recruiting

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

for
Colorectal Cancer, Pancreatic Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT06411691

Phase1, Recruiting

A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health

for
Sudan Virus Disease
Location: Boston MA, Washington D.C. DC, Lenexa KS
Sponsor: International AIDS Vaccine Initiative

Sex: All

Age: 18 - 50

Code: NCT07565090

Phase1, Recruiting

Converting HR+ Breast Cancer Into an Individualized Vaccine

for
Breast Cancer
Location: New York NY, Houston TX, Dallas TX
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 70+

Code: NCT03804944

Phase2, Recruiting

A Study of NeuroVax™, a Therapeutic TCR Peptide Vaccine for SPMS of Multiple Sclerosis

for
Secondary Progress Multiple Sclerosis, Multiple Sclerosis
Location: San Diego CA
Sponsor: Immune Response BioPharma, Inc.

Sex: All

Age: 18 - 50

Code: NCT02057159

Phase2, Phase3, Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial