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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer

for
Breast Cancer, Triple Negative Breast Cancer (TNBC),
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07276880

Phase2, Recruiting

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for
Pneumococcal Immunization, Healthy Volunteers
Location: Tampa FL, Spartanburg SC, Simpsonville SC,
Sponsor: Sanofi

Sex: All

Age: 0

Code: NCT07348692

Phase3, Recruiting

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non-Small Cell Lung Cancer,
Location: Montreal
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07261631

Phase1, Recruiting

Observational, Passive Surveillance Program to Collect Information on Women and Their Offspring Exposed to MenQuadfi® During Pregnancy, in United States (US)

for
Meningococcal Infection
Location: Swiftwater PA
Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All

Age: 0+

Code: NCT04843111

Recruiting

Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07191717

Phase2, Recruiting

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Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Pittsburgh PA, Irvine CA, Duarte CA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07156227

Phase1, Recruiting

Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

for
Pneumococcal Immunization, Healthy Volunteers
Location: Houston TX
Sponsor: Sanofi

Sex: All

Age: 0

Code: NCT06975878

Phase3, Recruiting

Rituximab, Vaccine Therapy, and GM-CSF in Treating Patients With Non-Hodgkin's Lymphoma

for
Lymphoma
Location: Nashville TN
Sponsor: Favrille

Sex: All

Age: 18+

Code: NCT00258336

Phase2, Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

for
Covid19
Location: Raleigh NC, Lenexa KS
Sponsor: Meissa Vaccines, Inc.

Sex: All

Age: 18 - 69

Code: NCT04798001

Phase1, Recruiting

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

for
Respiratory Syncytial Virus Immunization,
Location: Boston MA, Brookline MA, Methuen MA, East Greenwich RI,
Sponsor: Sanofi

Sex: All

Age: 60+

Code: NCT07734649

Phase1, Phase2, Recruiting

Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

for
Breast Cancer, Leptomeningeal Disease
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07694986

Phase2, Recruiting

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

for
Acne
Location: Jacksonville FL, Brandon FL, New Orleans LA, Encino CA
Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All

Age: 18 - 45

Code: NCT07013747

Phase1, Phase2, Recruiting

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

for
Melanoma (Skin)
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 0+

Code: NCT00085397

Phase2, Recruiting

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

for
Acne
Location: Brighton MA, Marlborough MA, Quebec, Sherbrooke,
Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All

Age: 18 - 45

Code: NCT06316297

Phase1, Phase2, Recruiting

Procurement of Blood Samples for a Biomedical Research Program on T Cell Functional Response to Chronic HBV Infection

for
Chronic Hepatitis B
Location: Richmond VA
Sponsor: Vaccine and Gene Therapy Institute, Florida

Sex: All

Age: 18+

Code: NCT02017587

Recruiting

A Phase I Cancer Vaccine Study for Patients With Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Mobile AL
Sponsor: Southern Cancer Center

Sex: Female

Age: 18 - 70+

Code: NCT00715832

Phase1, Recruiting

Seasonal Influenza Vaccine, Quadrivalent Versus Trivalent in Patients With Advanced Chronic Obstructive Pulmonary Disease

for
Chronic Obstructive Pulmonary Disease
Location: Phoenix AZ
Sponsor: Banner Health

Sex: All

Age: 50 - 64

Code: NCT02563184

Recruiting

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

for
Sickle Cell Disease
Location: New Brunswick NJ, Atlanta GA, Omaha NE, Houston TX
Sponsor: Sanofi

Sex: All

Age: 2 - 17

Code: NCT07247188

Phase3, Recruiting

A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations

for
SARS-CoV-2
Location: Richmond VA, Decatur GA, Atlanta GA, Gulfport MS,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 0+

Code: NCT06585241

Recruiting

Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age

for
Prevention of Pneumonic Plague Resulting From Aerosol Exposure to Yersinia Pestis,
Location: Cincinnati OH
Sponsor: Dynavax Technologies Corporation

Sex: All

Age: 18 - 55

Code: NCT07207408

Phase2, Not recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial