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Brain Cancer Clinical Trials

Browse 315 brain cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

for
Advanced Breast Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT04090567

Phase2, Recruiting

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

for
Primary Central Nervous System Lymphoma, Recurrent Cancer,
Location: Boston MA, New York NY
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04421560

Phase1, Phase2, Recruiting

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

for
Leukemia, High Risk Acute Lymphoblastic Leukemia,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0 - 25

Code: NCT06839456

Phase1, Phase2, Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD, Nashville TN, Chicago IL, Houston TX,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04830137

Phase1, Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for
Neuroendocrine Tumors Unresectable,
Location: Baltimore MD, Fairfax VA, Chapel Hill NC, Miami FL,
Sponsor: Perspective Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05636618

Phase1, Phase2, Recruiting

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Adrenoleukodystrophy National Registry Study

for
ALD (Adrenoleukodystrophy), Adrenoleukodystrophy,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0+

Code: NCT03789721

Recruiting

Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study

for
Grade I Meningioma, Grade II Meningioma, Grade III Meningioma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT04278118

Recruiting

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

for
Glioma, Medulloblastoma, Ependymoma, Glioblastoma
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161519

Phase1, Phase2, Recruiting

ECoG BMI for Motor and Speech Control

for
ALS, SCI - Spinal Cord Injury, Stroke, Multiple Sclerosis,
Location: San Francisco CA
Sponsor: Karunesh Ganguly

Sex: All

Age: 21+

Code: NCT03698149

Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for
High Grade Glioma, Meningioma, Embryonal Tumor, Medulloblastoma,
Location: Columbus OH, Cincinnati OH
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 4 - 39

Code: NCT05278208

Phase1, Phase2, Recruiting

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

for
Primary Central Nervous System Lymphoma,
Location: Boston MA
Sponsor: Lakshmi Nayak, MD

Sex: All

Age: 18+

Code: NCT04906096

Phase2, Recruiting

A Comparison of Healthcare Provider and Caregiver Perception of Discomfort in Advanced Cancer Patients Who Have a Hypoactive Delirium

for
Hypoactive Delirium
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05837039

Recruiting

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors

for
Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent,
Location: Grand Rapids MI, Austin TX
Sponsor: Medical University of Vienna

Sex: All

Age: 0 - 19

Code: NCT01356290

Phase2, Recruiting

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

for
Delirium, Epileptics, Neuroleptics
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05431595

Phase2, Phase3, Recruiting

Cerebrospinal Fluid Biomarkers for Brain Tumors

for
Central Nervous System Neoplasm
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0+

Code: NCT04692324

Recruiting

International Rare Brain Tumor Registry

for
Astroblastoma, BCOR ITD Sarcoma, CNS Sarcoma,
Location: Washington D.C. DC, Akron OH, Cincinnati OH, Chicago IL,
Sponsor: Children's National Research Institute

Sex: All

Age: 0 - 45

Code: NCT05697874

Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

for
Central Nervous System Neoplasms, Glioblastoma,
Location: Bethesda MD
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04541082

Phase1, Recruiting

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

for
CNS Tumors, Meningioma, Esthesioneuroblastoma, Hemangioblastoma,
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 70+

Code: NCT04081701

Recruiting

Digoxin Medulloblastoma Study

for
Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH
Location: Hartford CT, The Bronx NY, Baltimore MD,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 1 - 30

Code: NCT06701812

Phase2, Recruiting

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

for
Lymphoma, Primary Central Nervous System Lymphoma
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06475235

Phase1, Recruiting