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Dry Eye Disease Clinical Trials

Browse 38 Dry Eye Disease clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber

for
Dry Eye Disease (DED)
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT07430735

Recruiting
Active & Responsive

2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD

for
Dry Eye Disease, oGVHD
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT04946721

Recruiting
Active & ResponsiveNew

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

for
Fuchs Endothelial Corneal Dysfunction,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 20 - 70+

Code: NCT07780890

Recruiting
Active & Responsive

A Multicenter, Open-Label Study to Evaluate Perioperative Treatment of Dry Eye With Miebo® in Subjects Undergoing LASIK

for
Dry Eye Syndrome (DES), Dry Eye Disease (DED)
Location: Fargo ND, Sioux Falls SD, Bozeman MT
Sponsor: Vance Thompson Vision

Sex: All

Age: 18+

Code: NCT07650708

Recruiting
Active & Responsive

Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment

for
Dry Eye, Meibomian Gland Dysfunction
Location: Berkeley CA
Sponsor: University of California, Berkeley

Sex: All

Age: 18+

Code: NCT07606625

Recruiting

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Active & Responsive

Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Study

for
Dry Eye
Location: Houston TX
Sponsor: Neuro-Ophthalmology of Texas

Sex: All

Age: 18+

Code: NCT07566975

Recruiting

Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)

for
Dry Eye Disease
Location: Memphis TN
Sponsor: ORA, Inc.

Sex: All

Age: 18+

Code: NCT06178679

Phase3, Recruiting

The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free

for
Dry Eye Disease (DED)
Location: La Jolla CA
Sponsor: Gordon Schanzlin New Vision

Sex: All

Age: 18+

Code: NCT07745062

Recruiting

TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED)

for
Dry Eye Disease (DED)
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07732010

Recruiting

The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

for
Dry Eye Disease (DED)
Location: Fullerton CA
Sponsor: Southern California College of Optometry at Marshall B. Ketchum University

Sex: All

Age: 18+

Code: NCT06655441

Recruiting

Study for Remote Investigation of Evaporative Dry Eye Disease

for
Evaporative Loss Dry Eye Disease
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06976515

Recruiting

Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery

for
Dry Eye Disease (DED)
Location: Sioux Falls SD
Sponsor: Vance Thompson Vision

Sex: All

Age: 22+

Code: NCT07155057

Recruiting

Ocular Complications From Cancer Therapy - Patient Registry and Biobank

for
Graft Versus Host Disease in Eye, Ocular Complications,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06874283

Recruiting

Senofilcon A Lenses in Moderate to Severe Dry Eye Disease

for
Moderate to Severe Dry Eye Disease
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT04096898

Recruiting
New

BL-RX01-TFSTAB-1402

for
Dry Eye
Location: Sioux Falls SD
Sponsor: Vance Thompson Vision

Sex: All

Age: 18+

Code: NCT07790211

Recruiting
New

Long-term Effects of Acoltremon vs. Control in Dry Eye Disease

for
Dry Eye
Location: Louisville KY
Sponsor: The Eye Care Institute

Sex: All

Age: 18+

Code: NCT07659626

Recruiting

Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

for
Dry Eye Syndrome, Infectious Keratoconjunctivitis,
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT04198740

Recruiting

Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye

for
Dry Eye, Eye Diseases, Eyes Dry Chronic
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT07413172

Phase2, Recruiting

Evaluation of a Novel Ocular Lubricating Eye Drop

for
Dry Eye Syndrome (DES)
Location: Waterloo
Sponsor: Pleryon Therapeutics (Hangzhou) Limited

Sex: All

Age: 18+

Code: NCT07593404

Recruiting

Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses

for
Dry Eye
Location: Kingston PA
Sponsor: Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists

Sex: All

Age: 22+

Code: NCT07510620

Recruiting

What are Dry Eye Disease clinical trials?

Dry eye disease can range from occasional irritation to a persistent, disruptive problem, and clinical trials reflect that range, testing things like eye drops, devices, and lifestyle-based strategies to improve tear quality and ease discomfort. Researchers also use these studies to better understand what's driving symptoms, since causes can include aging, environmental factors, or autoimmune conditions.

The importance of clinical trials in Dry Eye Disease research

Millions of people deal with dry eye symptoms, often without knowing there's real research behind what actually helps. Dry eye clinical trials matter here because the condition is often tied to autoimmune disorders, so findings in this space can inform care well beyond eye comfort alone.

Who can participate in Dry Eye Disease clinical trials?

Types of Dry Eye Disease clinical trials

How long do dry eye disease clinical trials typically last?

How to enroll in a clinical trial for Dry Eye Disease