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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

for
Graft-Versus-Host Disease, Graft-versus-leukemia,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 60

Code: NCT00001529

Recruiting
Active & Responsive

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for
Lymphoid Leukemia
Location: Boston MA, The Bronx NY, New Castle DE, Baltimore MD,
Sponsor: Stanford University

Sex: All

Age: 0 - 26

Code: NCT05865301

Recruiting
Active & Responsive

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

for
Acute Leukemia, Myelodysplastic Syndrome
Location: Palo Alto CA
Sponsor: Laguna Biotherapeutics, Inc.

Sex: All

Age: 1 - 39

Code: NCT07573111

Phase1, Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia (AML)
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT07464951

Phase1, Recruiting

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Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Boston MA, Atlanta GA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase1, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

for
Chronic Lymphocytic Leukemia, B-cell Malignancies
Location: Florham Park NJ, Miami Beach FL, Pittsburgh PA,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT07271667

Phase2, Recruiting
Active & Responsive

A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT07392242

Phase2, Recruiting
Active & Responsive

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

for
Acute Myeloid Leukemia, Pediatric AML
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 30

Code: NCT07059975

Early_phase1, Recruiting
Active & Responsive

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

for
Chronic Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06817720

Phase2, Recruiting
Active & Responsive

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

for
T-cell Prolymphocytic Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07311746

Phase1, Phase2, Recruiting
Active & Responsive

CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML

for
Refractory Acute Myeloid Leukemia (AML),
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT07347418

Phase1, Recruiting
Active & Responsive

Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)

for
Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV,
Location: Toronto, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 18

Code: NCT07509151

Phase3, Recruiting
Active & Responsive

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0 - 6

Code: NCT06609928

Phase1, Recruiting
Active & Responsive

Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia, TP53
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT07008638

Phase1, Phase2, Recruiting
Active & Responsive

A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

for
CLL / SLL, CLL (Chronic Lymphocytic Leukemia),
Location: Chapel Hill NC, Columbus OH, Cincinnati OH,
Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All

Age: 18+

Code: NCT06708897

Phase1, Recruiting
Active & Responsive

Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

for
Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT07071155

Early_phase1, Recruiting
Active & Responsive

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT07428707

Early_phase1, Recruiting
Active & Responsive

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia

for
Chronic Myeloid Leukemia,
Location: The Bronx NY, New York NY, Toronto, Houston TX,
Sponsor: Enliven Therapeutics

Sex: All

Age: 18+

Code: NCT05304377

Phase1, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial