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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery

for
Skull Base Neoplasms, Cerebrospinal Fluid Leakage,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT05898074

Recruiting

CT-95 in Advanced Cancers Associated With Mesothelin Expression

for
Mesothelin-Expressing Tumors, Epithelial Ovarian Cancer,
Location: Hackensack NJ, Philadelphia PA, Grand Rapids MI,
Sponsor: Context Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06756035

Phase1, Recruiting

Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors

for
Atrial Fibrillation, Supraventricular Arrhythmia,
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT05643235

Recruiting

Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer

for
Head and Neck Cancer, Gynecologic Cancer, Cervical Cancer,
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 18+

Code: NCT05850663

Recruiting

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

for
Solid Tumor
Location: Fairfax VA, Myrtle Beach SC, Durham NC, Miami FL,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06874335

Phase1, Recruiting

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A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for
Ovarian Cancer, Breast Cancer, Endometrial Cancer,
Location: Boston MA, Philadelphia PA, Falls Church VA, Buffalo NY,
Sponsor: NextCure, Inc.

Sex: All

Age: 18+

Code: NCT06774963

Phase1, Recruiting

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

for
Liver Cancer
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT04933435

Recruiting

Palbociclib and Pembrolizumab In Central Nervous System Metastases

for
Metastatic Malignant Neoplasm to Brain,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT02896335

Phase2, Recruiting

MR/TRUS Fusion Guided Prostate Biopsy

for
Prostate Disease, Elevated Prostate Specific Antigen,
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Male

Age: 18+

Code: NCT04026763

Recruiting

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

for
Lymphoma, Non-Hodgkin, Relapsed Non Hodgkin Lymphoma,
Location: Boston MA, Bronx NY, New York NY, Hackensack NJ,
Sponsor: Caribou Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT04637763

Phase1, Recruiting

Breast Cancer Resiliency Through Exercise Program (B-REP)

for
Breast Cancer Female
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Female

Age: 18+

Code: NCT06100263

Recruiting

A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

for
Lymphoma, B-Cell, Lymphoma, T-Cell
Location: New York NY, Sarasota FL, Denver CO
Sponsor: Step Pharma, SAS

Sex: All

Age: 18+

Code: NCT05463263

Phase1, Phase2, Recruiting

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

for
Peritoneal Mesothelioma, Peritoneal Carcinomatosis,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04847063

Phase1, Recruiting

Community-Based Physical Activity Intervention for Underserved Cancer Survivors

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06206863

Recruiting

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

for
Glioma, Malignant Brain Neoplasm, Meningioma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06650163

Phase1, Recruiting

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

for
Brain Tumor
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT03286335

Recruiting

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

for
Metastatic Cancer
Location: Chicago IL, Madison WI
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT04295863

Phase1, Recruiting

Primary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters

for
Venous Thromboembolism, Cancer
Location: Halifax, Levis, Greenfield Park, Montreal, Ottawa,
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05029063

Phase3, Recruiting

Neurocutaneous Melanocytosis Registry

for
Cutaneous Melanocytic Neoplasm,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT04548817

Recruiting

MRg-NIRS Imaging System Breast Cancer Trial

for
Breast Cancer
Location: Lebanon NH
Sponsor: Keith D. Paulsen

Sex: Female

Age: 18 - 70+

Code: NCT06400563

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer