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Oncology Clinical Trials

Browse 9,171 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for
Metastatic Prostate Cancer
Location: New York NY, Hackensack NJ, Philadelphia PA, Tampa FL,
Sponsor: AstraZeneca

Sex: Male

Age: 18 - 70+

Code: NCT06267729

Phase1, Phase2, Recruiting

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05118789

Phase1, Phase2, Recruiting

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

for
Breast Cancer, TNBC - Triple-Negative Breast Cancer,
Location: Westbury NY, New Brunswick NJ, Baltimore MD, Miami FL,
Sponsor: Processa Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06568692

Phase2, Recruiting

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

for
B-cell Acute Lymphoblastic Leukemia,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 0 - 30

Code: NCT04544592

Phase1, Phase2, Recruiting

Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers

for
Metastatic Breast Cancer, Triple Negative Breast Cancer,
Location: Durham NC, Buffalo NY, Atlanta GA, Lexington KY,
Sponsor: Kathy Miller

Sex: All

Age: 18+

Code: NCT05846789

Phase2, Recruiting

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Erector Spinae Block for Thoracic Surgery

for
Pulmonary Neoplasm, Pulmonary Cancer, Thoracic Diseases,
Location: Washington D.C. DC
Sponsor: George Washington University

Sex: All

Age: 18 - 70+

Code: NCT05521789

Recruiting

Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma

for
Carcinoma, Hepatocellular, Liver Cell Carcinoma
Location: The Bronx NY, New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT05366829

Phase2, Recruiting

Peer Counseling for Weight Loss

for
Breast Cancer
Location: Detroit MI
Sponsor: Wayne State University

Sex: Female

Age: 18 - 70+

Code: NCT00120029

Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00801489

Phase2, Recruiting

Safety Study of CAT-8015 Immunooxin in Patients With HCL With Advance Disease

for
Leukemia, Hairy Cell Leukemia, HCL
Location: Bethesda MD
Sponsor: Cambridge Antibody Technology

Sex: All

Age: 18+

Code: NCT00462189

Phase1, Recruiting

Improve Outcomes for Older Allogeneic Transplant Recipients

for
Allogeneic Transplantation
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 60+

Code: NCT05612789

Recruiting

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

for
Lung Cancer
Location: Boston MA, Bronx NY, Durham NC, Detroit MI, Atlanta GA,
Sponsor: Hummingbird Diagnostics

Sex: All

Age: 50 - 70+

Code: NCT05987189

Recruiting

Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, New York NY, Houston TX, Irving TX,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06167317

Phase1, Recruiting

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

for
HIV Infections, Hepatitis B
Location: Wilmington NC
Sponsor: Syneos Health

Sex: Female

Age: 12 - 60

Code: NCT00404989

Recruiting

A Comparison of 2 Standard Doses of Bevacizumab in Combination With Chemotherapy in Epithelial Ovarian Cancer

for
Ovarian Cancer, Platinum-resistant Ovarian Cancer
Location: Abbotsford, Vancouver
Sponsor: British Columbia Cancer Agency

Sex: Female

Age: 18+

Code: NCT04787289

Phase2, Recruiting

Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder

for
RUNX1 Familial Platelet Disorder
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT06414889

Phase1, Recruiting

A Study of CPI-613 With Gemcitabine and Nab-paclitaxel for Patients With Advanced or Metastatic Pancreatic Cancer

for
Pancreatic Cancer, Metastatic Pancreatic Cancer
Location: Summit NJ, Morristown NJ
Sponsor: Atlantic Health System

Sex: All

Age: 18+

Code: NCT03435289

Phase1, Recruiting

Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry

for
Oligometastasis, Metastatic Cancer
Location: Raleigh NC, Cary NC, Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT04085029

Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for
Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID
Location: Ney York NY, New Brunswick NJ, Philadelphia PA,
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT03567889

Phase3, Recruiting

Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma

for
Penile Carcinoma
Location: Tampa FL, Houston TX
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male

Age: 18+

Code: NCT05526989

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer