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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Talazoparib and Thoracic RT for ES-SCLC

for
Lung Cancer, Small-Cell Lung Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04170946

Phase 1, Recruiting

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Weymouth MA, Boston MA, Brighton MA, Methuen MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT02269592

Recruiting

Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue

for
Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreatic Cyst
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT03140592

Recruiting

Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer

for
Non-small Cell Lung Cancer
Location: Waterford CT, Guilford CT, Hamden CT, New Haven CT,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT04210492

Phase 1, Phase 2, Recruiting

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

for
Breast Cancer, Quality of Life
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female

Age: 65+

Code: NCT05472792

Phase 2, Recruiting

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Improving Communication and Building a Stronger Medical Home Among Spanish-speaking Families

for
Leukemia, Non Hodgkin Lymphoma
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 0 - 22

Code: NCT05425992

Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

for
Lung Cancer, NSCLC, Brain Metastases
Location: Columbus OH, Aurora CO, Stanford CA
Sponsor: Joshua Palmer

Sex: All

Age: 18+

Code: NCT05987644

Phase 1, Phase 2, Recruiting

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

for
Head and Neck Cancer
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06477692

Phase 2, Recruiting

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

for
Breast Cancer, Stage III Breast Cancer, Breast Cancer Female,
Location: Boston MA, State College PA, Pittsburgh PA,
Sponsor: Dana-Farber Cancer Institute

Sex: Female

Age: 65+

Code: NCT05535192

Recruiting

Converting HR+ Breast Cancer Into an Individualized Vaccine

for
Breast Cancer
Location: New York NY, Houston TX, Dallas TX
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 70+

Code: NCT03804944

Phase 2, Recruiting

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC

for
Triple Negative Breast Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female

Age: 18+

Code: NCT06245889

Phase 2, Recruiting

Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy

for
Head and Neck Squamous Cell Carcinoma, Brain Metastases
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05996432

Early Phase 1, Recruiting

Virtual Rehabilitation for Cancer Survivors

for
Breast Cancer, Stage 0, Colorectal Cancer Stage I,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05898789

Recruiting

Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer

for
Metastatic Pancreatic Adenocarcinoma
Location: Tampa FL, Canton OH, Whittier CA
Sponsor: Eleison Pharmaceuticals LLC.

Sex: All

Age: 18+

Code: NCT01954992

Phase 3, Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

for
Metastatic Chondrosarcoma, Locally Advanced Chondrosarcoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06176989

Phase 2, Recruiting

Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED

for
Melanoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06548789

Phase 2, Recruiting

Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

for
Early Stage Breast Cancer
Location: Hartford CT, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 21 - 70+

Code: NCT04458532

Recruiting

Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by Progesterone

for
Polycystic Ovary Syndrome, Hyperandrogenism, Normal Puberty
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Female

Age: 7 - 14

Code: NCT01428089

Phase 1, Recruiting

Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies

for
Leukemia, Acute Lymphoblastic Leukemia
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 1 - 25

Code: NCT06408194

Phase 1, Recruiting

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

for
Multiple Myeloma, Smoldering, Multiple Myeloma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06055894

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer