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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Study of SGR-1505 in Mature B-Cell Neoplasms

for
Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL,
Location: Boston MA, Providence RI, The Bronx NY, New York NY,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT05544019

Phase1, Recruiting

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

for
CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia,
Location: Fort Myers FL, Mayfield Heights OH, Cleveland OH,
Sponsor: Frantz Viral Therapeutics, LLC

Sex: Female

Age: 25 - 70+

Code: NCT04098744

Phase2, Recruiting

Immune Effects in Patients Treated With Whole Breast Irradiation

for
Breast Cancer
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Female

Age: 45+

Code: NCT03567044

Recruiting

Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy

for
Ovarian Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT06083844

Phase2, Recruiting

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

for
Brain Tumor, Primary, Brain Metastases, Adult
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05480644

Recruiting

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Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

for
Cytomegalovirus Infections, Primary Immune Deficiency Disorder
Location: Valhalla NY, Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: New York Medical College

Sex: All

Age: 0 - 70+

Code: NCT03266640

Phase2, Recruiting

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

for
Endometrial Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05819892

Phase1, Recruiting

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

for
Large B-cell Lymphoma, Relapsed Non-Hodgkin Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06104592

Phase2, Recruiting

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

for
Major Depressive Disorder, Chronic Major Depression, Recurrent
Location: Austin TX
Sponsor: University of Texas at Austin

Sex: All

Age: 18 - 65

Code: NCT05892744

Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer

for
Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp,
Location: San Diego CA, Monrovia CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06342440

Recruiting

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

for
Acute Myeloid Leukemia
Location: Cleveland OH, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05834244

Phase1, Recruiting

FTT PET/CT in Metastatic Prostate Cancer

for
Prostate Cancer Metastatic
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Male

Age: 18+

Code: NCT05242744

Recruiting

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

for
Relapsed or Refractory Multiple Myeloma
Location: Boston MA, New York NY, Hillsborough NC,
Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT06375044

Phase1, Recruiting

A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer

for
Advanced Solid Tumor, Hepatocellular Carcinoma
Location: Montreal, Lexington VA, Orlando FL, Toronto,
Sponsor: TORL Biotherapeutics, LLC

Sex: All

Age: 18+

Code: NCT06005740

Phase1, Recruiting

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04151940

Recruiting

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

for
Recurrent Ovarian Cancer, Recurrent Fallopian Tube Cancer,
Location: Boston MA, New York NY, Richmond VA, Columbus OH,
Sponsor: Regeneron Pharmaceuticals

Sex: Female

Age: 18+

Code: NCT03564340

Phase1, Phase2, Recruiting

Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML

for
AML/MDS, Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: The Bronx NY, Houston TX
Sponsor: Montefiore Medical Center

Sex: All

Age: 18+

Code: NCT05986240

Phase1, Recruiting

Lurbinectedin in FET-Fused Tumors

for
Ewing Sarcoma, Desmoplastic Small Round Cell Tumor,
Location: Boston MA, New York NY, Philadelphia PA, Ann Arbor MI,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10+

Code: NCT05918640

Phase1, Phase2, Recruiting

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

for
Lymphomas, B-cell Lymphomas
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05773040

Phase1, Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Pittsburgh PA, Houston TX, Newport Beach CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT05372640

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer