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Oncology Clinical Trials

Browse 9,028 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1
New

B7-H3.CD28Z.CART in Solid Tumors

for
Pediatric Solid Tumor, Neuroblastoma
Location: Boston MA
Sponsor: Robbie Majzner

Sex: All

Age: 0 - 30

Code: NCT07358260

Phase1, Recruiting
New

Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian Cancer

for
Ovarian Cancer
Location: New York NY, East Brunswick NJ, Los Angeles CA
Sponsor: Tubulis GmbH

Sex: Female

Age: 18+

Code: NCT07736937

Phase1, Phase2, Recruiting
New

PREDICTT Clinical Trial: Prospective Evaluation Of Pressure-Enabled Delivery And Alterations In CT-Based Tumor-To-Normal Liver Ratio And Tumor Dose Using The Trinav Infusion System

for
Tumor, Liver
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07444645

Recruiting
New

A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy

for
Breast Cancer
Location: Boston MA, Atlanta GA
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05646862

Phase3, Recruiting
New

A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer

for
Cancer, Medication Adherence
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 15 - 24

Code: NCT07223463

Recruiting

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New

First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Grand Rapids MI, San Antonio TX, Duarte CA
Sponsor: VelaVigo Bio Inc

Sex: All

Age: 18+

Code: NCT07700160

Phase1, Phase2, Recruiting
New

Unified Network for Integrated Fluid Collection at Yale

for
Molecular Residual Disease, Cancer
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07689864

Recruiting
New

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

for
Metastatic Biliary Tract Carcinoma, Metastatic Colon Carcinoma,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT07594626

Phase1, Phase2, Recruiting
New

Study of NXP900 With Lorlatinib in ALK+ Lung Cancer

for
ALK Positive, ALK Positive Non-small Cell Lung Cancer, NSCLC,
Location: Fairfax VA
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 0+

Code: NCT07784959

Phase1, Recruiting
New

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

for
Family History of Lung Cancer
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07600801

Recruiting
New

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07322341

Phase2, Recruiting
New

TLR9 Immunotherapy for Peritoneal Carcinomatosis

for
Malignant Ascites, Colorectal Adenocarcinoma,
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT07658196

Phase1, Recruiting
New

External Beam and Radioligand Radiotherapy for mCRPC

for
Prostate Cancer Metastatic Castration-Resistant
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Male

Age: 0+

Code: NCT07354594

Phase2, Recruiting
New

Assessing PI3K Gamma Inhibition With Azacitidine, Venetoclax and Eganelisib in Patients With Acute Myeloid Leukemia

for
Leukemia, Myeloid, Leukemia, Acute Myeloid Leukemia,
Location: Boston MA
Sponsor: Jacqueline Garcia, MD

Sex: All

Age: 18 - 70+

Code: NCT07439211

Phase1, Recruiting
New

BRIDGE-SIC Efficacy Trial

for
Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07735442

Recruiting
New

A Ph II Study of the TheraBionic P1 Device in Subjects With Hormone Positive Breast Cancer

for
HER2-negative Breast Cancer, Hormone Receptor Positive Tumor,
Location: Port Huron MI, Mount Clemens MI, Detroit MI, Lapeer MI,
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 22+

Code: NCT07227831

Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting
New

Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC

for
NSCLC, Non-small Cell Lung Cancer,
Location: Plantation FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07777822

Phase3, Recruiting
New

A Study of Romosozumab in People With Breast Cancer and Osteoporosis

for
Breast Cancer, Metastatic Breast Cancer (MBC)
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT07776613

Phase2, Recruiting
New

Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

for
Metastatic Bladder Cancer, Peripheral Neuropathy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07548476

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer