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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for
Advanced Cancer, Metastatic Cancer, Ovarian Cancer,
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Artios Pharma Ltd

Sex: All

Age: 18+

Code: NCT04657068

Phase 1, Phase 2, Recruiting

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

for
Solid Tumors, ER+ Breast Cancer,
Location: Detroit MI, St Louis MO, Dallas TX, Salt Lake City UT
Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All

Age: 18+

Code: NCT05490472

Phase 1, Phase 2, Recruiting

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05178472

Recruiting

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Austin TX, San Antonio TX, Scottsdale AZ
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT05094804

Phase 1, Phase 2, Recruiting

The Impact of COVID-19 on Pulmonary Procedures

for
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT05022446

Recruiting

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Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Miami FL
Sponsor: Florida International University

Sex: All

Age: 0 - 21

Code: NCT05857969

Phase 1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase 1, Phase 2, Recruiting

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

for
Hematological Malignancy, Solid Tumor Malignancy
Location: Baltimore MD, Charlotte NC, Cincinnati OH, Seattle WA
Sponsor: Century Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05768269

Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for
Locally Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Scarborough ME, Boston MA, Montreal, Philadelphia PA,
Sponsor: Turning Point Therapeutics, Inc.

Sex: All

Age: 0 - 25

Code: NCT04094610

Phase 1, Phase 2, Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 16+

Code: NCT05269381

Phase 1, Phase 2, Recruiting

Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

for
Urothelial Cancer, Cancer, Bladder Neoplasms,
Location: Burlington MA
Sponsor: Lahey Clinic

Sex: All

Age: 18+

Code: NCT00872495

Recruiting

Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma

for
Relapsed Cancer, Refractory Multiple Myeloma, Multiple Myeloma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05922501

Phase 2, Recruiting

Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06640010

Recruiting

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

for
Locally Advanced Malignant Solid Neoplasm,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT04515810

Recruiting

Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06709404

Recruiting

Home-Based Symptom Monitoring: Its Impact on Cancer Care Team Behaviors and Patient Outcomes

for
Cancer, Solid Tumor, Hematologic Malignancy
Location: Indianapolis IN, Martinsville IN
Sponsor: Community Cancer Care

Sex: All

Age: 18+

Code: NCT00300001

Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

for
Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05039801

Phase 1, Recruiting

Pan-tumor MRD Study

for
Muscle Invasive Bladder Urothelial Carcinoma, Esophageal Cancer,
Location: Shirley NY, Lancaster PA, Binghamton NY, York PA,
Sponsor: Paradigm Health

Sex: All

Age: 18+

Code: NCT06605404

Recruiting

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05098210

Phase 1, Recruiting

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Mineola NY, New York NY, Bethesda MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05687110

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer