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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma

for
Ependymoma, High Grade Gliomas
Location: Chicago IL
Sponsor: Cerenome

Sex: All

Age: 6 - 21

Code: NCT07061626

Phase1, Recruiting

The Impact of Structured Exercise on Brain Health in HIV Positive Individuals

for
HIV
Location: Montreal
Sponsor: McGill University

Sex: Male

Age: 35 - 70+

Code: NCT03053817

Recruiting
New

NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism

for
Primary Hyperparathyroidism
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07812649

Recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for
Basal Ganglia Germinoma, Diabetes Insipidus, Germinoma,
Location: Halifax, Scarborough ME, Boston MA, Providence RI,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT06368817

Phase2, Recruiting
New

Vorasidenib Maintenance for IDH Mutant Astrocytoma

for
IDH-mutant Grade 2 or 3 Astrocytoma
Location: Winnipeg
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT06809322

Phase3, Recruiting

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Uterine Lavage to Detect Ovarian Cancer Risk

for
BRCA Hereditary Ovarian Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: Female

Age: 18+

Code: NCT07772869

Recruiting

The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.

for
Fibroid Uterus
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: Female

Age: 18+

Code: NCT06536517

Phase2, Recruiting

Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes

for
Genetic Testing, BRCA1/2
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 25+

Code: NCT03396341

Recruiting
New

MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

for
Anxiety Disorders, Stress Disorders, Post-Traumatic,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: Female

Age: 18 - 70+

Code: NCT07540585

Recruiting

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for
Chronic Lymphocytic Leukaemia,
Location: Philadelphia PA, Columbus OH
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06651970

Recruiting

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma,
Location: Los Angeles CA, Sacramento CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18 - 70

Code: NCT05256641

Phase1, Phase2, Recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma,
Location: Charlotte NC, Memphis TN, Tulsa OK, San Diego CA
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06390319

Phase2, Recruiting

A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)

for
Breast Cancer
Location: Washington DC
Sponsor: Georgetown University

Sex: Female

Age: 50 - 70+

Code: NCT02457117

Recruiting

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

for
Oropharyngeal Carcinoma,
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT03215719

Phase2, Recruiting

Rectal Cancer Shared Care

for
Rectal Cancer, Low Anterior Resection Syndrome
Location: Montreal
Sponsor: Jewish General Hospital

Sex: All

Age: 18+

Code: NCT04966819

Recruiting

Statins and Breast Cancer Biomarkers

for
Breast Cancer
Location: Boston MA, Burlington VT, Newark DE, Goldsboro NC,
Sponsor: University of Vermont

Sex: Female

Age: 35 - 55

Code: NCT00914017

Phase2, Recruiting

PrEP Intervention for People Who Inject Substances and Use Methamphetamine

for
HIV Infections
Location: San Francisco CA
Sponsor: San Francisco Department of Public Health

Sex: Male

Age: 18 - 65

Code: NCT04523519

Recruiting

Prehabilitation to Improve Cancer Surgery Outcomes

for
Gastrointestinal Cancer, Prehabilitation, Surgery,
Location: Toronto
Sponsor: Mount Sinai Hospital, Canada

Sex: All

Age: 18+

Code: NCT03502317

Recruiting

TFL vs MOSES Holmium Laser in the En-bloc Resection of Bladder Tumors

for
Urolithiasis of Bladder
Location: Thunder Bay
Sponsor: Thunder Bay Regional Health Research Institute

Sex: All

Age: 18+

Code: NCT06373419

Recruiting

Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

for
Chronic Phase Chronic Myelogenous Leukemia
Location: New York NY, Buffalo NY, Detroit MI, Milwaukee WI,
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT04838041

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer